Steven T. DeKosky, MD

 

Steven.Dekosky@neurology.ufl.edu

Dr. Steven DeKosky is the Aerts-Cosper Professor of Alzheimer’s Research at the University of Florida College of Medicine, and is Deputy Director of the McKnight Brain Institute. His basic research centers on structural and neurochemical changes in human brain in aging and dementia and effects of traumatic brain injury (TBI). Beginning trauma studies as a Principal Investigator in the University of Pittsburgh Brain Trauma Research Center in 1992, he studied similarities in the injury cascades of TBI and AD. Dr. DeKosky has served on and led numerous NIH review and advisory committees, and taught and mentored in clinical research training programs sponsored by the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS).


Dr. DeKosky was a member of the national Board of Directors of the Alzheimer’s Association from 1994 to 2002 (Board Vice Chair in 2001-2002), and again from 2003 to 2010. He served as Chair of the Section on Geriatrics of the American Academy of Neurology (AAN), and chaired the AAN Practice Parameters Committee for Early Detection, Diagnosis and Management of Dementia. He is the founding Chair of the Advisory Council of ISTAART, the International Society to Advance Alzheimer’s Disease Research and Treatment. He has testified multiple times before U.S. Senate Committees for greater research funding for Alzheimer’s disease, and has met with government officials in other countries as a consultant and advocate for programs and support for people with dementia.

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Research Interests

Dementia, especially Alzheimer’s Disease; diagnosis, treatment, prevention, neurochemistry, genetics, neuroimaging, epidemiology, neuropsychiatry.
Central Nervous System regeneration and response to injury
Traumatic Brain Injury and relationship to long-term neurological outcomes
Ethics, health policy, and clinical/biomarker aspects of preclinical assessment for dementia

Awards and Recognition

Invited Speaker, International Alzheimer’s Disease Conference, University of Hong Kong – 2016
Invited Speaker, Rotary Club, Wyndham Garden – 2016
70th Platinum Anniversary Edition of Who’s Who in America

Professional Affiliations

Alzheimer’s Association
American Board of Psychiatry and Neurology
American Academy of Neurology
American Neurological Association

Medical Education

University of Florida College of Medicine, Gainesville, FL – 1974

Internship

Johns Hopkins Hospital, Baltimore, MD – 1975

Residency

Neurology Residency, University of Florida, Gainesville, FL 1978

Fellowship

Neurochemistry, Clinical Neuroscience Research Center, University of Virginia Medical School, Charlottesville, VA – 1979

Select Publications

Dickstein DL, Pullman MY, Fernandez C, Short JA, Kostakoglu L, Knesaurek K, Soleimani L, Jordan BD, Gordon WA, Dams-O’Connor K, Delman BN, Wong E, Tang CY, DeKosky ST, Stone JR, Cantu RC, Sano M, Hof PR, Gandy S.  Cerebral [18F] T807/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy. Transl Psychiatry. 2016 Sep 27;6(9). PMID: 27676441.

Nadkarni NK, Perera S, Snitz BE, Mathis CA, Price J, Williamson JD, DeKosky ST, Klunk WE, Lopez OL. Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype. JAMA Neurol. 2017 Jan 1; 74(1); 82-90. PMID: 27842173.

Asken BM, Sullan MJ, Snyder AR, Houck ZM, Bryant VE, Hizel LP, McLaren ME, Dede DE, Jaffee MS, DeKosky ST, Bauer RM.Factors Influencing Clinical Correlates of Chronic Traumatic Encephalopathy (CTE): a   Review. Neuropsychol Rev. 2016 Dec;26(4):340-363. PMID: 27561662.

Pullman, M.Y., Dickstein, D.L., DeKosky, S.T., Gandy, S. Antemortem biomarker support for a diagnosis of clinically probable chronic traumatic encephalopathy. Mol Psychiatry 2017 Jan 10.  PMID: 28070125.

Lopez, O.L., Weissfeld, L., Kuller, L.H., Klunk, W.E., Mathis, C., Becker, J.T., Ives, D., Snitz, B., Fitzpatrick, A., Carlson, M., Rapp, S., Williamson, J., DeMattos, R., Tracy, R., Price, J., Kamboh, M.I. and DeKosky, S.T.  Plasma amyloid levels, brain amyloid deposition, and hippocampal volume in cognitively normal subjects.  JAMA Neurology, 2016 [In Press].

DeKosky, S.T., and Schneider, L. Preventing Dementia: Many issues and not enough time. JAMA Neuroogy 2017 [In Press]

Dr. DeKosky’s publications can be reviewed through the National Library of Medicine’s publication database.