S.H. Subramony, M.D.
Phone: (352) 273-5550
Fax: (352) 273-5575
Department of Neurology
Room L3-100, McKnight Brain Institute
1149 Newell Drive
Gainesville, FL. 32611
Dr. Subramony was serendipitously picked to rotate through a Neurology Department in India as soon as he finished medical school when such Departments were rare in that part of the world. He became fascinated and did not look back in terms of a Specialty to work in, despite the fact that he could have picked any, having graduated within the top 2% of his class in Delhi University. Dr Subramony trained in Neurology at the Cleveland Clinic in Cleveland, OH and then completed training in electromyography. He joined the faculty at University of Mississippi where by another serendipitous occurrence he developed an interest in genetic disorders thanks to the then Chair, Dr. Robert Currier. This also was the era of the Human Genome project and he was able to collaborate with many stalwart researchers around the country to identify and understand many gene defects leading to muscular and cerebellar diseases. This interest has continued to this day with the opportunity to bring translational research to patients in this field.
Dr. Subramony has clinical expertise in evaluating and treating many neuromuscular diseases with Specialty certifications in Neurology and Neuromuscular Medicine as well as being a member of the American Association of Neuromuscular and Electrodiagnostic Medicine. He has expertise in performing electromyography and autonomic testing as well as interpreting muscle biopsy findings.
Dr. Subramony’s current research interests center around many genetic diseases that are caused by a particular type of mutation called unstable repeat expansions. As a founding co-member of the Center for Neurogenetics, he interacts almost weekly with many excellent scientists in that center that have cutting edge lab programs in myotonic dystrophy and spinocerebellar ataxias. In addition, he has close collaboration with the Powell Gene Therapy Center.This allows him to bring many translational research studies to patients and has several clinical research projects including drug trials, imaging studies and biomarker development programs. The main thrust of these programs includes Friedreich ataxia, spinocerebellar ataxias and myotonic dystrophy. He participates in nationally organized, multi-center research efforts in these diseases.
Dr. Subramony enjoys teaching at all levels from students, to residents to fellows and graduate students. In particular he enjoys illustrating the connection between basic science discoveries and clinical issues.
Delhi University, 1972
McNeal Hospital. Berwyn, Illinois 1975
Cleveland Clinic, Cleveland OH 1980
Awards and Recognitions
Neuroscience Alumnus of the year (1992, Cleveland Clinic, Cleveland, OH)
Billy Guyton Professorship, University of Mississippi Medical Center
Charlotte Warmoth Professorship, UTMB, Galveston, TX
American Academy of Neurology
American Neurological Association
American Association of Neuromuscular and Electrodiagnostic Medicine
Degenerative Ataxias: challenges in clinical research. Subramony SH. Ann Clin Transl Neurol. 2016 Nov 17;4(1):53-60.
Clinical evaluation of eye movements in spinocerebellar ataxias: a prospective multicenter study. Moscovich M, Okun MS, Favilla C, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai V, Ying S, Zesiewicz T, Kuo SH, Mazzoni P, Bushara K, Xia G, Ashizawa T, Subramony SH.
Overview of autosomal dominant ataxias. Subramony SH. Handb Clin Neurol. 2012;103:389-98.
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3. Paulson HL, Perez MK, Trottier Y, Trojanowski JQ, Subramony SH, Das SS, Vig P, Mandel JL, Fischbeck KH, Pittman RN.
Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Zhuchenko O, Bailey J, Bonnen P, Ashizawa T, Stockton DW, Amos C, Dobyns WB, Subramony SH, Zoghbi HY, Lee CC. Nat Genet. 1997 Jan;15(1):62-9