Epilepsy Surgery

The specialists at the UF Comprehensive Epilepsy Program are experts in performing all the latest surgical techniques to treat epilepsy and seizure disorders. Using advanced stereotactic technology to pinpoint the location of the epileptic lesion, these procedures aim at removing the smallest possible amount of brain tissue to achieve control or to decrease the frequency and/or severity of seizures.

They include:

  • Anterior temporal lobectomy
  • Extratemporal resections
  • Hemispherectomy
  • Lesionectomy
  • Corpus callosotomy
  • Vagus nerve stimulation


Neurodiagnostic Modalities for Epilepsy Surgery

Click the picture below to download the Epilepsy Surgery PowerPoint Presentation

Phase 1

Primary Phase 1 Evaluation

Scalp VideoEEG monitoring

3T MRI of Brain


Additional Phase 1 Diagnostic Procedures


Functional MRI



Phase 1B Evaluation (if determined to be surgical candidate)

Wada Procedure

Neuropsychological Testing


Phase 2

If noninvasive Phase I evaluation does not definitively localize the epileptogenic region, the placement and use of intracranial electrodes is required

Invasive videoEEG monitoring

Cortical Mapping


Phase 3

University of Florida Comprehensive Epilepsy Program Epilepsy surgery for seizures from 1992-2010

Epilepsy Surgery

  • Cortical resection: removal of the seizure focus
  • Removal of abnormal tissue: vascular malformations, tumors, brain malformations
  • Corpus callsotomy: separate the 2 hemispheres/sides of the brain so seizures cannot spread as rapidly and extensively
  • Hemispherectomy: removal of one side of the brain usually in catastrophic pediatric epilepsy case