The primary focus of Dr. Bose’s research has been on understanding of motor neuroplasticity following neurorehabilitation using preclinical (rodent) models of neurotrauma (spinal cord and traumatic brain injuries), and neurodegenerative/neuro-autoimmune (e.g. MS) diseases. Major focus has been given on research to understanding of motor neuroplasticity and regeneration following innovative translational therapies (locomotor exercise, transcranial magnetic stimulation, and pharmacological therapies) on motor deficits (spasticity and gait), behavior abnormalities (pain, anxiety-like behaviors, and social behaviors), and their molecular mechanisms to find a novel targets for appropriate therapy. He is also interested in sensory and cognitive plasticity following neurotrauma and neurodegenerative/neuro-autoimmune diseases. Dr. Bose laboratory along with Dr. Thompson have developed and/or adapted several sensitive quantitative tools to understand fundamental physiological inhibitory processes that control sensory input to hindlimb muscle stretch reflexes. These processes usually alter following contusion injuries and neurodegerative diseases. Dr. Bose has joint appointment between the University of Florida (Department of Physiological Sciences, College of Veterinary Medicine, and Department of Neurology, College of Medicine) and the US Department of Veterans Affairs. His research program is supported by federal and nonfederal funding agencies.