Congratulations Drs Vedant Garg, Venkat Srikar Lavui, Grace Hey, Brett Winter, Marcos Santana Firme, Justin D. Hillard, Coralie DeHemptinne, Michael S. Okun and Joshua K. Wong on the publication of “Beyond Pallidal or Subthalamic Deep Brain Stimulation to Treat Dystonia,” which appears in the September issue of Tremor and other Hyperkinetic Movements.
Abstract
Deep brain stimulation of the subthalamic nucleus and globus pallidus internus is approved by the Food and Drug Administration for treating dystonia. Both targets have shown effectiveness in improving symptoms, but post-operative outcomes can vary significantly among patients. This variability has led researchers to explore alternative neuromodulation targets that might offer more consistent results. Emerging research has highlighted several promising new targets for DBS in dystonia. This review examines pre-clinical and clinical data on novel DBS targets for dystonia and explores non-invasive neuromodulation studies that shed light on the disease’s underlying pathological circuitry.