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Reengineering Deep Brain Stimulation for Movement Disorders: Emerging Technologies

Congratulations Drs. Gunduz, Foote and Okun on the publication of “Reengineering Deep Brain Stimulation for Movement Disorders: Emerging Technologies,” in Current Opinion in Biomedical Engineering’s September issue.   Abstract Deep brain stimulation (DBS) is a neurosurgical technique, which consists of continuous delivery of an electrical pulse through chronically implanted electrodes…

Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias

Congratulations Dr. Guangbin Xia and Dr. S.H. Subramony on the publication of “Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias,” which was published in Tremor and Other Hyperkinetic Movements.   Abstract Background: Postural tremor can sometimes occur in spinocerebellar ataxias (SCAs). However, the prevalence and clinical characteristics of postural tremor in…

Congratulations to Drs. Chuquilin and Wymer!

Congratulations to Drs. Chuquilin and Wymer on your recent editorial “Increasing Evidence for an Association Between Amyotrophic Lateral Sclerosis and Psychiatric Disorders” in JAMA Neurology.

Lewy Body Dementia Association (LBDA) Research Center of Excellence Grant

Melissa Armstrong M.D., MSc. Assistant Professor, Department of Neurology successfully led the application and effort for UF to have a Lewy Body Center of Excellence. Dr. Armstrong’s site will be publicly promoted by LBDA as one of the finest resources in the nation for LBD clinical care.

Welcome Pragya Prakash!

Pragya is a post doc in Dr. Rincon-Limas’ lab.  If you see Pragya, please welcome her to the team!  …

Management of Elevated Therapeutic Impedances on Deep Brain Stimulation Leads

Congratulations to Drs. Deeb and Okun on the publication of their case file “Management of Elevated Therapeutic Impedances on Deep Brain Stimulation Leads,” which was published in Tremor and Other Hyperkinetic Movements. Abstract Clinical Vignette: A 64-year-old male with a history of essential tremor with bilateral thalamic ventralis intermedius deep brain stimulation…

The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome.

Congratulations to Dr. Nikolaus McFarland on the publication of “The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome,” in the September issue of PLoS One.   Abstract Abnormal accumulation of α-synuclein (αSyn) has been linked to endoplasmic-reticulum (ER) stress, defective intracellular protein/vesicle trafficking, and cytotoxicity. Targeting factors…

RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2

Congratulations Dr. Guangbin Xia on the publication of “RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.”  This article was published in the September issue of Neuron. Summary Several microsatellite-expansion diseases are characterized by the accumulation of RNA foci and RAN…

The Ice Test to Differentiate Essential tremor from Parkinson’s disease tremor

Congratulations to Drs. Aparna Wagle Shukla, Michael Okun, and  David Vaillancourt on the publication of “The Ice Test to Differentiate Essential tremor from Parkinson’s disease tremor,” which was published in the September 8th issue of Clinical Neurophysiology. Introduction Essential tremor (ET) is characterized by bilateral postural and action tremor…