Cavernous Malformations Clinic at UF Neurology

Cavernous malformations, also called cavernous angiomas and cavernomas, are abnormal clusters of dilated blood vessels. The walls of these vessels are generally weak and are prone to leaking blood. These malformations can cause seizures, stroke symptoms, hemorrhages and headache. They can also remain asymptomatic and not require any treatment.

The size can range from microscopic to inches in diameter, cavernous malformations can be located anywhere in the body including the liver, rectum, kidney, eyes, nerves, spinal cord and brain. Those that develop in the brain or spinal cord, called cerebral cavernous malformations (CCM), are the most serious.

About one in 200 people have a cavernous malformation, affecting men and women almost equally and occurring in people of all races, sexes and ages. In some cases, these malformations may run in families and are inherited. There are genetic basis for CCM.

At UF Neurology and Neurosurgery, we are working closely with Angioma Alliance and Recursion pharmaceutical  to enroll patients into the SYCAMORE trial If you are interested in being seen for CCM and would like more information, please contact

Please watch the link about advances in Neurosurgical care of Cerebral Cavernous malformation from Dr. Gary Steinberg at Stanford Cavernous Malformation Center.