Acute Ischemic Stroke – GUT-ABI

Name: GUT-ABI (Gut microbiome in acute neurological injury: a prospective study)

Contact: Neringa May (Lead CRC, 843-298-2693), Dr. William Roth (PI)

Enrolling hours: M-F (daytime)

Diagnosis: AIS (currently only enrolling AIS, but plans for other dx later)

Inclusion:

  1. >= 18 years of age at admission;
  2. diagnosed with a primary injury of subarachnoid hemorrhage, acute ischemic stroke, intracranial hemorrhage, subdural hematoma, or traumatic brain injury;
  3. are admitted to the Neuromedicine Intensive Care Unit (NMICU) at UF Health;
  4. the patient or their legally authorized representative (LAR) are able to provide consent for study participation.

Exclusion:

  1. have had gastrointestinal tract surgery in the 3 months prior to admission (not including routine diagnostic procedures such as endoscopy and colonoscopy)
  2. have had any prior bowel resection
  3. have an active surgical feeding tube or diverting ostomy at time of admission
  4. have had prior or active rectal or anal pathology that would preclude rectal swab sampling
  5. are, or are suspected to be pregnant
  6. have been hospitalized for any acute brain injury in the 2 months prior to admission
  7. are enrolled in another clinical trial or have received an investigational agent in the 3 months prior to admission