Melissa Armstrong

Melissa Armstrong, MD, MSc, FAAN

Associate Professor Of Neurology, Director, Mangurian Clinical-Research Headquarters For Lewy Body Dementia

Department: MD-NEUROLOGY-MOVEMENT DISORDER
Business Phone: (352) 273-5550

About Melissa Armstrong

Dr. Melissa J. Armstrong, MD, MSc is the Director of the Mangurian Clinical-Research Headquarters for Lewy Body Dementia at the University of Florida. She joined the UF Department of Neurology in 2015.

Dr. Armstrong graduated from Illinois Wesleyan University in 1995 with a major in chemistry and a minor in philosophy. She completed medical school at the Stritch School of Medicine (Loyola University Chicago), where she subsequently completed a preliminary residency year in internal medicine and her neurology residency. Following her residency, she worked as a general neurologist at Loyola University Medical Center before pursuing fellowship training in movement disorders. Dr. Armstrong was a clinical and research fellow at the highly respected Morton & Gloria Shulman Movement Disorders Centre in Toronto, Ontario (Canada) from 2008 through 2011 where she was an Edmond J. Safra Fellow in Movement Disorders. She also completed an MSc in clinical epidemiology and health care research at the University of Toronto Institute for Health Policy Management and Evaluation. Dr. Armstrong worked as an assistant professor in the Division of Movement Disorders at the University of Maryland from 2012 until moving to the University of Florida in 2015. During this time, she co-authored the book, “Parkinson’s Disease: Improving Patient Care” (Oxford American Neurology Library 2014). She was also recognized as part of the American Academy of Neurology’s Emerging Leaders Forum (2013-2014). In addition to her work in the field of movement disorders, she serves as an evidence-based medicine methodology consultant for the American Academy of Neurology, working on their clinical practice guideline development program.

At the University of Florida, Dr. Armstrong directs the Mangurian Clinical-Research Headquarters for Lewy Body Dementia, one of 25 centers in the United States recognized as a Lewy Body Dementia Association Research Center of Excellence (2017 to current). She also serves on the Lewy Body Dementia Association Scientific Advisory Council. Dr. Armstrong’s Lewy body dementia research focuses on the lived experience of disease for individuals with Lewy body dementia and their families, ranging from patient and caregiver priorities for care to hospital outcomes to end-of-life experiences.

Accomplishments

Faculty Clinical Research Award
2016 · University of Florida Department of Neurology
Golden Hammer Award
2015 · University of Maryland Department of Neurology
American Academy of Neurology Emerging Leader
2013 · American Academy of Neurology

Board Certifications

  • Neurology
    American Board of Psychiatry and Neurology

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Dementia
  • Parkinson disease

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-2163-1907

Publications

2021
Biomarker Use for Dementia With Lewy Body Diagnosis: Survey of US Experts.
Alzheimer disease and associated disorders. 35(1):55-61 [DOI] 10.1097/WAD.0000000000000414. [PMID] 33009039.
2021
Suicide and Lewy body dementia: Report of a Lewy body dementia association working group.
International journal of geriatric psychiatry. 36(3):373-382 [DOI] 10.1002/gps.5462. [PMID] 33169435.
2021
Treatment of Parkinson’s Disease with Cognitive Impairment: Current Approaches and Future Directions.
Behavioral sciences (Basel, Switzerland). 11(4) [DOI] 10.3390/bs11040054. [PMID] 33920698.
2020
An evidence-based methodology for systematic evaluation of clinical outcome assessment measures for traumatic brain injury
PLOS ONE. 15(12) [DOI] 10.1371/journal.pone.0242811. [PMID] 33315925.
2020
Assessment of Parkinson disease quality measures on 12-month patient outcomes.
Neurology. Clinical practice. 10(1):58-64 [DOI] 10.1212/CPJ.0000000000000745. [PMID] 32190421.
2020
Caregiver-Reported Barriers to Quality End-of-Life Care in Dementia With Lewy Bodies: A Qualitative Analysis.
The American journal of hospice & palliative care. 37(9):728-737 [DOI] 10.1177/1049909119897241. [PMID] 31902223.
2020
Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction.
Frontiers in human neuroscience. 14 [DOI] 10.3389/fnhum.2020.583441. [PMID] 33240065.
2020
Common neurodegenerative disorders in the perioperative setting: Recommendations for screening from the Society for Perioperative Assessment and Quality Improvement (SPAQI).
Perioperative care and operating room management. 20 [DOI] 10.1016/j.pcorm.2020.100092. [PMID] 32577538.
2020
Dementia with Lewy bodies and Parkinson disease dementia: More different than similar?
Neurology. 94(20):858-859 [DOI] 10.1212/WNL.0000000000009433. [PMID] 32332128.
2020
Diagnosis and Treatment of Parkinson Disease: A Review.
JAMA. 323(6):548-560 [DOI] 10.1001/jama.2019.22360. [PMID] 32044947.
2020
Ethnoracial Differences in Lewy Body Diseases with Cognitive Impairment.
Journal of Alzheimer's disease : JAD. 77(1):165-174 [DOI] 10.3233/JAD-200395. [PMID] 32804137.
2020
How to identify, incorporate and report patient preferences in clinical guidelines: A scoping review
Health Expectations. 23(5):1028-1036 [DOI] 10.1111/hex.13099. [PMID] 32656807.
2020
Participation and consultation engagement strategies have complementary roles: A case study of patient and public involvement in clinical practice guideline development.
Health expectations : an international journal of public participation in health care and health policy. 23(2):423-432 [DOI] 10.1111/hex.13018. [PMID] 31884708.
2020
Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and adolescents with autism spectrum disorder: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
Neurology. 94(9):392-404 [DOI] 10.1212/WNL.0000000000009033. [PMID] 32051244.
2020
Research priorities of caregivers and individuals with dementia with Lewy bodies: An interview study.
PloS one. 15(10) [DOI] 10.1371/journal.pone.0239279. [PMID] 33027276.
2020
The Narrowing Path for Nilotinib and Other Potential Disease-Modifying Therapies for Parkinson Disease.
JAMA neurology. 77(3):295-297 [DOI] 10.1001/jamaneurol.2019.3983. [PMID] 31841588.
2020
Time for a New Image of Parkinson Disease.
JAMA neurology. 77(11):1345-1346 [DOI] 10.1001/jamaneurol.2020.2412. [PMID] 32716484.
2019
Barriers and facilitators of communication about off periods in Parkinson’s disease: Qualitative analysis of patient, carepartner, and physician Interviews.
PloS one. 14(4) [DOI] 10.1371/journal.pone.0215384. [PMID] 30998707.
2019
Cause of Death and End-of-Life Experiences in Individuals with Dementia with Lewy Bodies
Journal of the American Geriatrics Society. 67(1):67-73 [DOI] 10.1111/jgs.15608.
2019
Causes and outcomes of hospitalization in Lewy body dementia: A retrospective cohort study.
Parkinsonism & related disorders. 64:106-111 [DOI] 10.1016/j.parkreldis.2019.03.014.
2019
Communication About OFF Periods in Parkinson’s Disease: A Survey of Physicians, Patients, and Carepartners.
Frontiers in neurology. 10 [DOI] 10.3389/fneur.2019.00892. [PMID] 31481924.
2019
Developing the Disorders of Consciousness Guideline and Challenges of Integrating Shared Decision-Making Into Clinical Practice.
The Journal of head trauma rehabilitation. 34(3):199-204 [DOI] 10.1097/HTR.0000000000000496. [PMID] 31058760.
2019
End-of-life experiences in dementia with Lewy bodies: Qualitative interviews with former caregivers.
PloS one. 14(5) [DOI] 10.1371/journal.pone.0217039. [PMID] 31145749.
2019
Improving patient-centred care for persons with Parkinson’s: Qualitative interviews with care partners about their engagement in discussions of “off” periods.
Health expectations : an international journal of public participation in health care and health policy. 22(3):555-564 [DOI] 10.1111/hex.12884. [PMID] 30977262.
2019
Lewy Body Dementias
Continuum (Minneapolis, Minn.). 25(1):128-146 [DOI] 10.1212/CON.0000000000000685. [PMID] 30707190.
2019
Patient Stakeholder Versus Physician Preferences Regarding Amyloid PET Testing.
Alzheimer disease and associated disorders. 33(3):246-253 [DOI] 10.1097/WAD.0000000000000311. [PMID] 31058683.
2019
Practice guideline update summary: Vaccine-preventable infections and immunization in multiple sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
Neurology. 93(13):584-594 [DOI] 10.1212/WNL.0000000000008157. [PMID] 31462584.
2019
Recognizing and treating atypical Parkinson disorders.
Handbook of clinical neurology. 167:301-320 [DOI] 10.1016/B978-0-12-804766-8.00016-9. [PMID] 31753139.
2019
Responsiveness to Change of the Montreal Cognitive Assessment, Mini-Mental State Examination, and SCOPA-Cog in Non-Demented Patients with Parkinson’s Disease.
Dementia and geriatric cognitive disorders. 47(4-6):187-197 [DOI] 10.1159/000496454. [PMID] 31315127.
2019
Shared decision making in mild cognitive impairment.
Neurology. Clinical practice. 9(2):160-164 [DOI] 10.1212/CPJ.0000000000000576. [PMID] 31041132.
2019
Tackling the imposter phenomenon to advance women in neurology.
Neurology. Clinical practice. 9(2):155-159 [DOI] 10.1212/CPJ.0000000000000607. [PMID] 31041131.
2019
Virtual Support Groups for Informal Caregivers of Individuals With Dementia: A Scoping Review.
Alzheimer disease and associated disorders. 33(4):362-369 [DOI] 10.1097/WAD.0000000000000349. [PMID] 31567144.
2018
Approach to assessing and using clinical practice guidelines.
Neurology. Clinical practice. 8(1):58-61 [DOI] 10.1212/CPJ.0000000000000417. [PMID] 29517067.
2018
Comprehensive systematic review summary: Treatment of cerebellar motor dysfunction and ataxia: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
Neurology. 90(10):464-471 [DOI] 10.1212/WNL.0000000000005055. [PMID] 29440566.
2018
Evidence in focus: Nusinersen use in spinal muscular atrophy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
Neurology. 91(20):923-933 [DOI] 10.1212/WNL.0000000000006502. [PMID] 30315070.
2018
Identifying priority outcomes that influence selection of disease-modifying therapies in MS.
Neurology. Clinical practice. 8(3):179-185 [DOI] 10.1212/CPJ.0000000000000449. [PMID] 30105155.
2018
Impact of patient involvement on clinical practice guideline development: a parallel group study.
Implementation science : IS. 13(1) [DOI] 10.1186/s13012-018-0745-6. [PMID] 29661195.
2018
Practice guideline update recommendations summary: Disorders of consciousness: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research.
Neurology. 91(10):450-460 [DOI] 10.1212/WNL.0000000000005926. [PMID] 30089618.
2018
Progressive Supranuclear Palsy: an Update.
Current neurology and neuroscience reports. 18(3) [DOI] 10.1007/s11910-018-0819-5. [PMID] 29455271.
2018
Understanding, Impact, and Communication of “Off” Periods in Parkinson’s Disease: A Scoping Review.
Movement disorders clinical practice. 5(5):461-470 [DOI] 10.1002/mdc3.12672. [PMID] 30515435.
2017
Dementia with Lewy bodies advances: A new consensus report.
Neurology. 89(1):18-19 [DOI] 10.1212/WNL.0000000000004071. [PMID] 28592452.
2017
Discordance Between Physician Assessment and Patient-Reported Depressive Symptoms in Parkinson Disease
Journal of Geriatric Psychiatry and Neurology. 30(4):191-195 [DOI] 10.1177/0891988717710335.
2017
Framework for enhancing clinical practice guidelines through continuous patient engagement.
Health expectations : an international journal of public participation in health care and health policy. 20(1):3-10 [DOI] 10.1111/hex.12467. [PMID] 27115476.
2017
Hospitalization and rehospitalization in Parkinson disease patients: Data from the National Parkinson Foundation Centers of Excellence.
PloS one. 12(7) [DOI] 10.1371/journal.pone.0180425. [PMID] 28683150.
2017
Improving email strategies to target stress and productivity in clinical practice.
Neurology. Clinical practice. 7(6):512-517 [DOI] 10.1212/CPJ.0000000000000395. [PMID] 29431178.
2017
Naturalistic study of guideline implementation tool use via evaluation of website access and physician survey.
BMC medical informatics and decision making. 17(1) [DOI] 10.1186/s12911-016-0404-2. [PMID] 28086771.
2017
Patient involvement in guidelines is poor five years after institute of medicine standards: review of guideline methodologies.
Research involvement and engagement. 3 [DOI] 10.1186/s40900-017-0070-2. [PMID] 29062544.
2017
Practice guideline summary: Reducing brain injury following cardiopulmonary resuscitation: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
Neurology. 88(22):2141-2149 [DOI] 10.1212/WNL.0000000000003966. [PMID] 28490655.
2017
Recommendations for patient engagement in guideline development panels: A qualitative focus group study of guideline-naïve patients.
PloS one. 12(3) [DOI] 10.1371/journal.pone.0174329. [PMID] 28319201.
2017
Recommendations for patient engagement in guideline development panels: A qualitative focus group study of guideline-naïve patients.
PloS one. 12(3) [DOI] 10.1371/journal.pone.0174329. [PMID] 28319201.
2017
Shared decision-making in stroke: an evolving approach to improved patient care.
Stroke and vascular neurology. 2(2):84-87 [DOI] 10.1136/svn-2017-000081. [PMID] 28959495.
2017
The Case for Antipsychotics in Dementia with Lewy Bodies.
Movement disorders clinical practice. 4(1):32-35 [DOI] 10.1002/mdc3.12383. [PMID] 30713945.
2017
Value Assessment at the Point of Care: Incorporating Patient Values throughout Care Delivery and a Draft Taxonomy of Patient Values.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 20(2):292-295 [DOI] 10.1016/j.jval.2016.11.008. [PMID] 28237212.
2016
Patient engagement and shared decision-making: What do they look like in neurology practice?
Neurology. Clinical practice. 6(2):190-197 [PMID] 27104070.
View on: PubMed

Grants

Jan 2021 ACTIVE
Characterizing Cognitive Fluctuations in Lewy Body Dementia to Improve Care and Research
Role: Other
Funding: UF FOU
Sep 2020 ACTIVE
Identifying Factors Predicting ACcurately End-of-Life in Dementia with Lewy Bodies and Promoting Quality End-of-Life Experiences: the PACE-DLB Study
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2020 ACTIVE
F022983 – UF Parkinson's Disease/Movement Disorders Fund
Role: Principal Investigator
Funding: UF FOU
Jun 2020 ACTIVE
1Florida Alzheimers Disease Research Center
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
May 2020 ACTIVE
Communication of Dementia Diagnoses: Investigating Patient, Family, and Physician Experiences and Developing Best Practices
Role: Principal Investigator
Funding: FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER
Feb 2020 – May 2020
Prevalence and Demographics of Multiple Sclerosis in the OneFlorida Data Trust
Role: Other
Funding: NATL MULTIPLE SCLEROSIS SOC
Jan 2020 ACTIVE
Lewy Body Dementia: Mangurian
Role: Principal Investigator
Funding: UF FOU
Oct 2019 ACTIVE
LBDA RCOE Program
Role: Principal Investigator
Funding: LEWY BODY DEMENTIA ASSOC
Oct 2018 – Sep 2019
University of Florida Collaboration as LBDA Research Center of Excellence- Year 2
Role: Principal Investigator
Funding: LEWY BODY DEMENTIA ASSOC
Jul 2018 – Jun 2020
Investigating Patterns of Care for Dementia with Lewy Bodies in Florida
Role: Other
Funding: AMER ACAD OF NEUROLOGY
Oct 2017 – Sep 2018
University of Florida Collaboration as LBDA Research Center of Excellence
Role: Principal Investigator
Funding: LEWY BODY DEMENTIA ASSOC
Sep 2015 – Jun 2020
Enhancing Clinical Guideline Development via Patient and Stakeholder
Role: Principal Investigator
Funding: AGCY HEALTHCARE RES AND QUALITY
Aug 2015 ACTIVE
University of Florida – Mt. Sinai Medical Center AD Research Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA

Education

MD
2003 · Loyola University Medical Center

Contact Details

Phones:
Business:
(352) 273-5550