Stephan Eisenschenk

Stephan Eisenschenk, MD

Clinical Associate Professor

Department: MD-NEUROLOGY-EPILEPSY
Business Phone: (352) 273-5550

About Stephan Eisenschenk

Stephan Eisenschenk MD is an Associate Professor of Neurology for the University of Florida’s Department of Neurology. He attended the University of Florida as an undergraduate in the Medical Honors Program and graduated from the University of Florida College of Medicine in 1993. He then completed his Residency, Fellowship, in Clinical Neurophysiology in Epilepsy and Sleep Medicine at the University of Florida and has been on faculty at UF Health since 1998. He is one of only a few physicians nationally board-certified in Clinical Neurophysiology and Sleep Medicine providing complete assessment of both his patients and the neurodiagnostic studies he interprets with over 20 years of clinical and research experience. In 2016, Dr. Eisenschenk was appointed Director of the North Florida/South Georgia VAMC Epilepsy Center of Excellence for the evaluation of our veterans with epilepsy and the possible relationship with traumatic brain injury. His clinical interests are epilepsy and sleep disorders focusing on improvement of cognitive and physical performance.  His research utilizes neurophysiology and neuroimaging modalities to assess cognitive and physical dysfunction to determine the effects of neurological disorders on driving performance.

Teaching Profile

Courses Taught
2018
BMS6812 Intro Clin Med 2
2021
MDC7800 Neurology Clerkship

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Epilepsy
  • Sleep disorders
  • Traumatic Brain Injury

Publications

Academic Articles
2024
Early vigabatrin to augment GABAergic pathways in post-anoxic status epilepticus.
Epilepsy & behavior : E&B. 160 [DOI] 10.1016/j.yebeh.2024.110082. [PMID] 39393141.
2024
EEG Infrastructure Within the Veterans Administration: A Survey.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. [DOI] 10.1097/WNP.0000000000001132. [PMID] 39531283.
2024
Obstructive Sleep Apnea and Stroke: Determining the Mechanisms Behind their Association and Treatment Options.
Translational stroke research. 15(2):239-332 [DOI] 10.1007/s12975-023-01123-x. [PMID] 36922470.
2024
Tiagabine-induced encephalopathy suppressed by vagus nerve stimulation: A case report.
Epilepsy & behavior reports. 28 [DOI] 10.1016/j.ebr.2024.100709. [PMID] 39295735.
2023
Duration of Prophylactic Levetiracetam After Surgery for Brain Tumor: A Prospective Randomized Trial.
Neurosurgery. 92(1):68-74 [DOI] 10.1227/neu.0000000000002164. [PMID] 36156532.
2022
Pregabalin for Recurrent Seizures in Critical Illness: A Promising Adjunctive Therapy, Especially for cyclic Seizures.
Neurocritical care. 37(1):140-148 [DOI] 10.1007/s12028-022-01459-6. [PMID] 35217998.
2020
Incidental Findings during an Overnight Polysomnography in a Young Girl with Excessive Daytime Sleepiness.
Annals of the American Thoracic Society. 17(10):1323-1325 [DOI] 10.1513/AnnalsATS.202005-468CC. [PMID] 33000962.
2020
Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy.
Neurology. 95(9):e1244-e1256 [DOI] 10.1212/WNL.0000000000010154. [PMID] 32690786.
2018
An Examination of Pain’s Relationship to Sleep Fragmentation and Disordered Breathing Across Common Sleep Disorders
Pain Medicine. 19(8):1516-1524 [DOI] 10.1093/pm/pnx211. [PMID] 29025100.
2017
Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy.
Epilepsia. 58(6):994-1004 [DOI] 10.1111/epi.13740. [PMID] 28398014.
2017
Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas.
Epilepsia. 58(6):1005-1014 [DOI] 10.1111/epi.13739. [PMID] 28387951.
2017
Motor Impairments in Transient Ischemic Attack Increase the Odds of a Subsequent Stroke: A Meta-Analysis.
Frontiers in neurology. 8 [DOI] 10.3389/fneur.2017.00243. [PMID] 28638365.
2015
Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography.
Epilepsia. 56(6):959-67 [DOI] 10.1111/epi.13010. [PMID] 25988840.
2015
Long-Term Treatment With Responsive Brain Stimulation in Adults With Refractory Partial Seizures
Neurology. 84(8):810-817 [DOI] 10.1212/WNL.0000000000001280. [PMID] 25616485.
2014
A Riemannian framework for matching point clouds represented by the Schrödinger distance transform.
Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. 2014:3756-3761 [PMID] 25821394.
2014
Homicide during postictal psychosis.
Epilepsy & behavior case reports. 2:118-20 [DOI] 10.1016/j.ebcr.2014.04.001. [PMID] 25667886.
2014
Intracranial hypotension masquerading as nonconvulsive status epilepticus: report of 3 cases.
Journal of neurosurgery. 120(3):624-7 [DOI] 10.3171/2013.7.JNS112308. [PMID] 23971956.
2014
Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial.
Epilepsia. 55(3):432-41 [DOI] 10.1111/epi.12534. [PMID] 24621228.
2013
Assessing the driving performance of a person with epilepsy presurgery and postsurgery.
The American journal of occupational therapy : official publication of the American Occupational Therapy Association. 67(3):e24-9 [DOI] 10.5014/ajot.2013.006569. [PMID] 23597697.
2013
Electroencephalogram effects of armodafinil: comparison with behavioral alertness.
Journal of clinical pharmacology. 53(10):1058-71 [DOI] 10.1002/jcph.143. [PMID] 23913585.
2012
Associations between clinical tests and simulated driving performance in persons with epilepsy.
Epilepsy & behavior : E&B. 23(3):241-6 [DOI] 10.1016/j.yebeh.2011.12.019. [PMID] 22341958.
2012
Construction of a neuroanatomical shape complex atlas from 3D MRI brain structures.
NeuroImage. 60(3):1778-87 [DOI] 10.1016/j.neuroimage.2012.01.095. [PMID] 22305953.
2012
Evidence-based review on epilepsy and driving.
Epilepsy & behavior : E&B. 23(2):103-12 [DOI] 10.1016/j.yebeh.2011.11.015. [PMID] 22227593.
2012
Pharmacokinetic-Pharmacodynamic Modeling of Armodafinil: Effects On Alertness and Electroen-Cephalogram of Sleep Deprived Adults
Clinical Pharmacology & Therapeutics. 91:S7-S8
2012
The role of perfusion CT in identifying stroke mimics in the emergency room: a case of status epilepticus presenting with perfusion CT alterations.
International journal of emergency medicine. 5(1) [DOI] 10.1186/1865-1380-5-4. [PMID] 22264341.
2011
Atypical Rasmussen’s encephalitis treated with temporal lobectomy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 18(2):287-90 [DOI] 10.1016/j.jocn.2010.05.011. [PMID] 21163652.
2011
Mixture of segmenters with discriminative spatial regularization and sparse weight selection.
Medical image computing and computer-assisted intervention : MICCAI … International Conference on Medical Image Computing and Computer-Assisted Intervention. 14(Pt 3):595-602 [PMID] 22003748.
2011
Population Pharmacokinetics and Pharmacodynamics of Armodafinil: Effects On Electroencephalogram and Alertness of Sleep Deprived Adults
. 51
2010
Construction of neuroanatomical shape complex atlas from 3D brain MRI.
Medical image computing and computer-assisted intervention : MICCAI … International Conference on Medical Image Computing and Computer-Assisted Intervention. 13(Pt 3):65-72 [PMID] 20879384.
2010
Group-wise Point-set registration using a novel CDF-based Havrda-Charvát Divergence.
International journal of computer vision. 86(1):111-124 [PMID] 20221321.
2010
Is antiepileptic drug use related to depression and suicidal ideation among patients with epilepsy?
Epilepsy & behavior : E&B. 19(3):494-500 [DOI] 10.1016/j.yebeh.2010.08.030. [PMID] 20880757.
2009
How Important Is Invasive Ictal Recording in Patients With Itractable Tle and Normal Mri?
Epilepsia. 50
2009
Is Antiepileptic Drug Use Associated With Suicidality in Patients With Epilepsy?
Epilepsia. 50
2009
Quetiapine improves visual hallucinations in Parkinson disease but not through normalization of sleep architecture: results from a double-blind clinical-polysomnography study.
The International journal of neuroscience. 119(12):2196-205 [DOI] 10.3109/00207450903222758. [PMID] 19916848.
2009
Seizure recurrence following epilepsy surgery: is post-operative EEG helpful?
Seizure. 18(3):193-6 [DOI] 10.1016/j.seizure.2008.09.003. [PMID] 18948038.
2008
Diagnosis of nonconvulsive status epilepticus (NCSE) in adults with altered mental status: clinico-electroencephalographic considerations.
American journal of electroneurodiagnostic technology. 48(1):11-37 [PMID] 18459630.
2008
Simultaneous nonrigid registration of multiple point sets and atlas construction.
IEEE transactions on pattern analysis and machine intelligence. 30(11):2011-22 [DOI] 10.1109/TPAMI.2007.70829. [PMID] 18787248.
2007
Kernel Fisher discriminant for shape-based classification in epilepsy.
Medical image analysis. 11(1):79-90 [PMID] 17157051.
2007
Simultaneous registration and parcellation of bilateral hippocampal surface pairs for local asymmetry quantification.
IEEE transactions on medical imaging. 26(4):471-8 [PMID] 17427734.
2006
Joint registration and segmentation of neuroanatomic structures from brain MRI.
Academic radiology. 13(9):1104-11 [PMID] 16935722.
2006
Superior divisional third cranial nerve paresis: clinical and anatomical observations of 2 unique cases.
Archives of neurology. 63(5):771-6 [PMID] 16682550.
2006
Treatment with oxcarbazepine during pregnancy.
The neurologist. 12(5):249-54 [PMID] 16990737.
2004
Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation.
Neurology. 63(6):1124-6 [PMID] 15452317.
2003
Dietary carbamazepine administration decreases liver pyruvate carboxylase activity and biotinylation by decreasing protein and mRNA expression in rats.
The Journal of nutrition. 133(7):2119-24 [PMID] 12840165.
2002
Botulinum toxin-induced paralysis of frontotemporal muscles improves seizure focus localization.
Neurology. 58(2):246-9 [PMID] 11805252.
2002
Progressive dementia and hypersomnolence with dream-enacting behavior: oneiric dementia.
Archives of neurology. 59(4):630-4 [PMID] 11939899.
2001
Lateralization of temporal lobe foci: depth versus subdural electrodes.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 112(5):836-44 [PMID] 11336899.
2001
Proximal myotonic myopathy: clinical, neuropathologic, and molecular genetic features.
Annals of clinical and laboratory science. 31(2):140-6 [PMID] 11337902.
1999
Adult-onset seizures: clinical solutions to a challenging patient work-up.
Geriatrics. 54(11):18-9, 22 [PMID] 10570654.
1999
Reduced density of parvalbumin- and calbindin D28-immunoreactive neurons in experimental cortical dysplasia.
Epilepsy research. 37(1):63-71 [PMID] 10515176.
1999
Strategies for successful management of older patients with seizures.
Geriatrics. 54(12):31, 34, 39-40 passim [PMID] 10605434.
1999
Topographic differences in task-dependent facilitation of magnetic motor evoked potentials.
Neurology. 52(3):537-40 [PMID] 10025783.
1998
The effect of LINAC stereotactic radiosurgery on epilepsy associated with arteriovenous malformations.
Stereotactic and functional neurosurgery. 71(2):51-61 [PMID] 10087469.
1995
Hippocampal volumetrics differentiate patients with temporal lobe epilepsy and extratemporal lobe epilepsy.
Archives of neurology. 52(8):819-24 [PMID] 7639634.

Grants

Nov 2021 – Apr 2024
Preoperative sleep spindles and delirium in Alzheimer's Disease
Role: Other
Funding: ALZHEIMERS ASSO
Sep 2016 – Aug 2020
Motor Control Deficits Following Transient Ischemic Attack
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Jul 2006 – Apr 2016
Repsonsive Neurostimulator (RNS) System Pivotal- A Clinical Investigation
Role: Principal Investigator
Funding: NEUROPACE INC

Education

MD
1993 · University of Florida, Gainesville

Contact Details

Phones:
Business:
(352) 273-5550
Addresses:
Business Mailing:
PO Box 100236
GAINESVILLE FL 32610
Business Street:
L3-100, UFBI
GAINESVILLE FL 32611