Giridhar Kalamangalam, MD, DPhil
Professor & Chief
Department:
MD-NEUROLOGY-EPILEPSY
Business Phone:
(352) 294-5188
Business Email:
gkalamangalam@ufl.edu
About Giridhar Kalamangalam
I am a Wilder Family endowed professor and division chief of epilepsy at the University of Florida College of Medicine. I was recruited by UF Health to my current position in September 2017.
Born and raised in India, I completed medical school at the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in Puducherri. I was a Rhodes scholar at Oxford University in England, where I earned a master’s degree in applied mathematics and a research doctorate in mathematical biology. I received my clinical training in internal medicine by rotation in various hospitals in the British National Health Service, and completed a general neurology residency at the Institute of Neurological Sciences in Glasgow. I was fellowship trained in epilepsy and EEG at the Cleveland Clinic.
My career has been devoted to the care of patients with epilepsy, along with research in the science in and around epilepsy. My publications have appeared in multiple peer-reviewed journals, and my work has been funded by the National Institute of Neurological Disorders and Stroke, as well as the American Epilepsy Society, among others.
Accomplishments
Fellow
2017
·
American Epilepsy Society
Top Doctor
2015-2016
·
Houstonia magazine
Fellow
2013
·
American Clinical Neurophysiology Society
Fellow
2011
·
Royal College of Physicians (London)
Fellow
2011
·
Royal College of Physicians and Surgeons (Glasgow)
Teaching Profile
Courses Taught
2019
GMS7794 Neuroscience Seminar
2021
MDC7800 Neurology Clerkship
Board Certifications
-
Completion of Training (Neurology)Postgraduate Medical Education and Training Board (UK)
-
DiplomateAmerican Board of Clinical Neurophysiology
-
MembershipRoyal College of Physicians (UK)
Clinical Profile
Epilepsy in adults, particularly refractory presentations; epilepsy surgery; clinical neurophysiology; brain mapping
Specialties
- Neurology
Areas of Interest
- Epilepsy
- Magnetoencephalography (MEG)
Research Profile
Epilepsy imaging; cortical neurophysiology; brain dynamics
Areas of Interest
- Integrative neuroscience
- Neuroimaging Methods
- Neurophysiology
- Physico-mathematical models
Publications
Academic Articles
2025
Amygdalar volume asymmetry informs laterality in temporal lobe epilepsy: MRI-SEEG study
Seizure: European Journal of Epilepsy.
126:58-63
[DOI] 10.1016/j.seizure.2025.02.006.
2025
Gradients in signal complexity of sleep-wake intracerebral EEG
PLOS ONE.
20(3)
[DOI] 10.1371/journal.pone.0320648.
[PMID] 40163484.
2025
Nontumoral Amygdalar Enlargement in Tumoral Epilepsy
World Neurosurgery.
197
[DOI] 10.1016/j.wneu.2025.123949.
[PMID] 40164441.
2024
Buna Joe “BJ” Wilder, MD (1929–2023)
Neurology.
102(8)
[DOI] 10.1212/wnl.0000000000209404.
2024
Laser Ablation of Periventricular Nodular Heterotopia for Medically Refractory Epilepsy.
Annals of neurology.
96(6):1174-1184
[DOI] 10.1002/ana.27059.
[PMID] 39297387.
2024
Learn how to interpret and use intracranial EEG findings
Epileptic Disorders.
26(1):1-59
[DOI] 10.1002/epd2.20190.
2024
Pearls & Oy-sters: Mesial Temporal Seizures in the Absence of the Mesial Temporal Lobe
Neurology.
102(2)
[DOI] 10.1212/wnl.0000000000208012.
2024
Prognostic value of the 5-SENSE Score to predict focality of the seizure-onset zone as assessed by stereoelectroencephalography: a prospective international multicentre validation study.
BMJ neurology open.
6(2)
[DOI] 10.1136/bmjno-2024-000765.
[PMID] 39175939.
2024
The SEEG Wave.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
41(5):397-398
[DOI] 10.1097/WNP.0000000000001095.
[PMID] 38935650.
2023
Identification and classification of pathology and artifacts for human intracranial cognitive research.
NeuroImage.
270
[DOI] 10.1016/j.neuroimage.2023.119961.
[PMID] 36848970.
2022
ONE-TIME PAROXYSM of ARTISTIC TALENT in FOCAL EPILEPSY.
Neurocase.
28(3):335-336
[DOI] 10.1080/13554794.2022.2117631.
[PMID] 36031874.
2022
Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury.
Frontiers in human neuroscience.
16
[DOI] 10.3389/fnhum.2022.813387.
[PMID] 35308605.
2022
Stereotactic EEG Practices: A Survey of United States Tertiary Referral Epilepsy Centers.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
39(6):474-480
[DOI] 10.1097/WNP.0000000000000794.
[PMID] 33181594.
2021
Functional Connectivity in Dorsolateral Frontal Cortex: Intracranial Electroencephalogram Study
Brain Connectivity.
11(10):850-864
[DOI] 10.1089/brain.2020.0816.
2021
Neurophysiological brain mapping of human sleep-wake states.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
132(7):1550-1563
[DOI] 10.1016/j.clinph.2021.03.014.
[PMID] 34034085.
2020
A neurophysiological brain map: Spectral parameterization of the human intracranial electroencephalogram.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
131(3):665-675
[DOI] 10.1016/j.clinph.2019.11.061.
[PMID] 31978851.
2020
Cognitive and functional status in late-onset Lennox-Gastaut syndrome: Variation on a classic phenotype.
Epilepsy & behavior : E&B.
102
[DOI] 10.1016/j.yebeh.2019.106660.
[PMID] 31770718.
2020
Could the 2017 ILAE and the four-dimensional epilepsy classifications be merged to a new “Integrated Epilepsy Classification”?
Seizure.
78:31-37
[DOI] 10.1016/j.seizure.2020.02.018.
[PMID] 32155575.
2020
Extracranial Interictal and Ictal EEG in sEEG Planning
Neurosurgery Clinics of North America.
31(3):345-371
[DOI] 10.1016/j.nec.2020.03.008.
2020
From theory to practice: Critical points in the 2017 ILAE classification of epileptic seizures and epilepsies
Epilepsia.
61(2):350-353
[DOI] 10.1111/epi.16426.
2019
Classification of paroxysmal events and the four-dimensional epilepsy classification system.
Epileptic disorders : international epilepsy journal with videotape.
21(1):1-29
[DOI] 10.1684/epd.2019.1033.
[PMID] 30782582.
2019
Critique of the 2017 epileptic seizure and epilepsy classifications.
Epilepsia.
60(6):1032-1039
[DOI] 10.1111/epi.14699.
[PMID] 30924146.
2019
Montages for Noninvasive EEG Recording.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
36(5):330-336
[DOI] 10.1097/WNP.0000000000000546.
[PMID] 31490450.
2019
The classification of paroxysmal events and the 4-dimensional epilepsy classification
JAMA neurology.
21(1):1-29
2018
Ictal-Interictal Continuum.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
35(4):274-278
[DOI] 10.1097/WNP.0000000000000447.
[PMID] 29979285.
2018
Interictal Epileptiform Discharge Detection in EEG in Different Practice Settings.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
35(5):375-380
[DOI] 10.1097/WNP.0000000000000492.
[PMID] 30028830.
2018
Mutual Information in Frequency and Its Application to Measure Cross-Frequency Coupling in Epilepsy
IEEE Transactions on Signal Processing.
66(11):3008-3023
[DOI] 10.1109/TSP.2018.2821627.
2017
A simple clinical score for prediction of nonepileptic seizures
Epilepsy & Behavior.
50-52
[DOI] 10.1016/j.yebeh.2017.09.005.
2017
A simple clinical score for prediction of nonepileptic seizures.
Epilepsy & behavior : E&B.
77:50-52
[DOI] 10.1016/j.yebeh.2017.09.005.
[PMID] 29111502.
2017
Characteristics of EEG Interpreters Associated With Higher Interrater Agreement.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
34(2):168-173
[DOI] 10.1097/WNP.0000000000000344.
[PMID] 27662336.
2017
Focal Changes to Human Electrocorticography With Drowsiness: A Novel Measure of Local Sleep.
The Journal of neuropsychiatry and clinical neurosciences.
29(3):236-247
[DOI] 10.1176/appi.neuropsych.16060120.
[PMID] 28121257.
2017
Prolonged Blood-Brain Barrier Disruption Following Laser Interstitial Ablation in Epilepsy: A Case Series with a Case Report of Postablation Optic Neuritis.
World neurosurgery.
104:467-475
[DOI] 10.1016/j.wneu.2017.05.009.
[PMID] 28502693.
2017
The interictal mesial temporal lobe epilepsy network
Epilepsia.
59(1):244-258
2016
A unified statistical model for the human electrocorticogram.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
127(12):3564-3573
[DOI] 10.1016/j.clinph.2016.06.027.
[PMID] 27449472.
2016
Focal cortical dysplasia and heterochromia of the iris.
Postgraduate medical journal.
92(1089)
[DOI] 10.1136/postgradmedj-2015-133809.
[PMID] 26850502.
2016
Identifying seizure onset zone from causal connectivity inferred using directed information
IEEE Journal of Selected Topics in Signal Processing.
10(7):1267-1283
2016
Intracranial evaluation and laser ablation for epilepsy with periventricular nodular heterotopia.
Seizure.
41:211-6
[DOI] 10.1016/j.seizure.2016.06.019.
[PMID] 27461957.
2016
Reactivation of visual-evoked activity in human cortical networks.
Journal of neurophysiology.
115(6):3090-100
[DOI] 10.1152/jn.00724.2015.
[PMID] 26984423.
2016
Stereo-EEG Implantation Strategy.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
33(6):483-489
[PMID] 27918343.
2016
Surgical Resection for Epilepsy Following Cerebral Gunshot Wounds.
World neurosurgery.
95:276-284
[DOI] 10.1016/j.wneu.2016.08.041.
[PMID] 27546337.
2016
Teaching NeuroImages: De novo absence status epilepticus in an adult.
Neurology.
86(17)
[DOI] 10.1212/WNL.0000000000002603.
[PMID] 27164648.
2015
Periodic Lateralized Epileptiform Discharges and Afterdischarges: Common Dynamic Mechanisms.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
32(4):331-40
[DOI] 10.1097/WNP.0000000000000173.
[PMID] 25710632.
2014
An inter-ictal EEG spectral metric for temporal lobe epilepsy lateralization
.
108(10):1748-1757
2014
An interictal EEG spectral metric for temporal lobe epilepsy lateralization.
Epilepsy research.
108(10):1748-57
[DOI] 10.1016/j.eplepsyres.2014.09.002.
[PMID] 25270401.
2014
Dynamic mechanisms underlying afterdischarge: a human subdural recording study.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
125(7):1324-38
[DOI] 10.1016/j.clinph.2013.11.027.
[PMID] 24365519.
2014
Focal cortical thickness correlates of exceptional memory training in Vedic priests.
Frontiers in human neuroscience.
8
[DOI] 10.3389/fnhum.2014.00833.
[PMID] 25368566.
2014
Proposal: different types of alteration and loss of consciousness in epilepsy.
Epilepsia.
55(8):1140-4
[DOI] 10.1111/epi.12595.
[PMID] 24981417.
2014
Stereotactic laser ablation of epileptogenic peri-ventricular nodular heterotopia
.
108(3):547-554
2014
Stereotactic laser ablation of epileptogenic periventricular nodular heterotopia.
Epilepsy research.
108(3):547-54
[DOI] 10.1016/j.eplepsyres.2014.01.009.
[PMID] 24518890.
2013
Difference in central and peripheral recovery in a patient with severe axonal motor neuropathy and central nervous system involvement and review of literature.
Journal of clinical neuromuscular disease.
14(3):110-3
[DOI] 10.1097/CND.0b013e3182852542.
[PMID] 23492462.
2013
Difference in central and peripheral recovery in a patient with severe axonal motor neuropathy and CNS involvement and review of the literature
.
14(3):110-113
2013
Intravenous ketamine for the treatment of refractory status epilepticus: a retrospective multicenter study.
Epilepsia.
54(8):1498-503
[DOI] 10.1111/epi.12247.
[PMID] 23758557.
2013
Noninvasive predictors of subdural grid seizure localization in children with nonlesional focal epilepsy
Journal of Clinical Neurology.
30(1):45-50
2013
Noninvasive predictors of subdural grid seizure localization in children with nonlesional focal epilepsy.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
30(1):45-50
[DOI] 10.1097/WNP.0b013e31827edca4.
[PMID] 23377441.
2012
Can cerebral microbleeds cause an acute stroke syndrome?
Neurology. Clinical practice.
2(2):91-92
[DOI] 10.1212/CPJ.0b013e31825ab82d.
[PMID] 30123674.
2012
Hemispheric epilepsy
.
79(13)
2012
Olanzapine-induced EEG changes reversed by lamotrigine
.
15(4):313-314
2012
Olanzapine-induced electroencephalographic changes reversed by lamotrigine.
Annals of Indian Academy of Neurology.
15(4):313-4
[DOI] 10.4103/0972-2327.104345.
[PMID] 23349602.
2012
Oxygen-enhanced MRI in temporal lobe epilepsy: diagnosis and lateralization.
Epilepsy research.
98(1):50-61
[DOI] 10.1016/j.eplepsyres.2011.08.014.
[PMID] 21917423.
2012
Oxygen-enhanced MRI: A novel modality for temporal lobe epilepsy diagnosis and lateralization
.
98:50-61
2012
Quality assessment of electroencephalography obtained from a “dry electrode” system.
Journal of neuroscience methods.
208(2):134-7
[DOI] 10.1016/j.jneumeth.2012.05.011.
[PMID] 22633894.
2012
Teaching neuroimages: unilateral clubbing in hemiplegia.
Neurology.
78(19)
[DOI] 10.1212/WNL.0b013e3182553cab.
[PMID] 22565573.
2011
Asymmetric scalp electromyogram: a common and accurate lateralizing sign in motor seizures.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
28(5):512-9
[DOI] 10.1097/WNP.0b013e318231c01f.
[PMID] 21946364.
2010
Temporal lobe white matter asymmetry and language laterality in epilepsy patients.
NeuroImage.
49(3):2033-44
[DOI] 10.1016/j.neuroimage.2009.10.055.
[PMID] 19874899.
2009
Hypergraphia in temporal lobe epilepsy
.
12:193-194
2009
Hypergraphia in temporal lobe epilepsy.
Annals of Indian Academy of Neurology.
12(3):193-4
[DOI] 10.4103/0972-2327.56323.
[PMID] 20174504.
2009
Noninvasive correlates of subdural grid electrographic outcome.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
26(5):333-41
[DOI] 10.1097/WNP.0b013e3181baaab9.
[PMID] 20168131.
2007
Neuroimaging and neurophysiology of periodic lateralized epileptiform discharges: observations and hypotheses.
Epilepsia.
48(7):1396-405
[PMID] 17386051.
2007
What you see is not what you get: believing patient-reported seizure counts.
Archives of neurology.
64(11):1565-6
[PMID] 17998438.
2002
Myelopathy from intracranial dural arteriovenous fistula.
Journal of neurology, neurosurgery, and psychiatry.
72(6):816-8
[PMID] 12023434.
2002
Periodic breathing at high altitude.
IMA journal of mathematics applied in medicine and biology.
19(4):293-313
[PMID] 12828366.
2002
Spontaneous intracranial hypotension.
Archives of neurology.
59(6)
[PMID] 12056942.
2001
Migrainous brain stem disturbance in Norrie disease: case report.
Journal of neurology, neurosurgery, and psychiatry.
70(6):815-6
[PMID] 11430297.
2001
Runner-up in the young physician’s section of the Gowers’ prize 2000. Epilepsy and the physical basis of consciousness.
Seizure.
10(7):484-91
[PMID] 11749104.
2000
The role of the central chemoreceptor in causing periodic breathing.
IMA journal of mathematics applied in medicine and biology.
17(2):147-67
[PMID] 10994511.
1993
A mathematical analysis of the Grodins model of respiratory control.
IMA journal of mathematics applied in medicine and biology.
10(4):249-80
[PMID] 8133130.
Grants
Jun 2022
ACTIVE
Multiscale Dynamics of the Frontotemporal Connectome in Refractory Epilepsy
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Feb 2018
– Jun 2019
Advancing Diagnosis and Functional Localization in Focal Epilepsy with Oxygen-Enhanced MRI
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Education
Epilepsy & EEG fellowship
2003-2004
·
Cleveland Clinic
Residency – Neurology (CCT)
2000-2005
·
Institute of Neurological Sciences, Glasgow
MRCP
1996-1998
·
Royal College of Physicians (UK)
MSc; DPhil
1989-1995
·
University of Oxford
Internship
1989
·
JIPMER Hospital
MBBS (medical school)
1983-1989
·
Jawaharlal Institute, India
Contact Details
Phones:
- Business:
- (352) 294-5188
Emails:
- Business:
- gkalamangalam@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100236
GAINESVILLE FL 32610 - Business Street:
-
1149 NEWELL DR RM L3 100
GAINESVILLE FL 32610