Michael S Okun

Michael S Okun, MD

Chair And Professor Of Neurology

Department: MD-NEUROLOGY-ADMIN/EDUC
Business Phone: (352) 294-5400
Business Email: okun@neurology.ufl.edu

About Michael S Okun

Michael S. Okun received his M.D. with honors from the University of Florida. He was fellowship trained by Mahlon DeLong, Jerrold Vitek and Ray Watts at Emory University in Atlanta GA before moving to found the movement disorders program at the University of Florida. He is currently Chair of Neurology, Professor and Executive Director of the Norman Fixel Institute for Neurological Diseases at the University of Florida Health College of Medicine. The UF institute he co-founded with Kelly D. Foote, M.D. is unique in that it is comprised of over 100 interdisciplinary faculty members from diverse areas of campus, all of whom are dedicated to care, outreach, education and research. Dr. Okun was instrumental in the construction of a one-stop patient-centered clinical-research experience for national and international patients seeking care at the University of Florida. This change in care and research delivery has since been named the service and science hub model of care. The UF based center draws national and international visitors interested in deploying this innovative clinical-research model. Dr. Okun has served as the National Medical Director for the Parkinson’s Foundation since 2006 and as the Medical Advisor for Tyler’s Hope for a Dystonia Cure. He has been supported by grants from the National Institutes of Health, the Smallwood Foundation, the Tourette Association of America, the Parkinson Alliance, the Bachmann-Strauss Foundation, the Parkinson’s Foundation, and the Michael J. Fox Foundation. Dr. Okun has an active research career exploring non-motor basal ganglia brain features and currently holds two NIH R01 grants and several foundation grants exploring various aspects of deep brain stimulation and neuromodulation. Dr. Okun has been an integral part of some of the pioneering studies exploring the cognitive, behavioral, and mood effects of brain stimulation and since 2005 his laboratory has been working to uncover the electrical brain signals associated with human tic. He has also partnered with Dr. Ayse Gunduz and Kelly Foote to develop a first generation of closed loop adaptive deep brain stimulation approaches. Dr. Okun was the founding PI for the International Database and Public Registry for Tourette Deep Brain Stimulation. He and his group have contributed data to support the FDA approval of several device related approaches now used to treat human disease. Dr. Okun holds the Adelaide Lackner Professorship in Neurology and has published over 400 peer-reviewed articles. He is a poet (Lessons From the Bedside, 1995) and his book, Parkinson’s Treatment: 10 Secrets to a Happier Life, was translated into over 20 languages. Dr. Okun was recognized in a 2015 White House ceremony by the Obama administration as a Champion of Change for Parkinson’s Disease.

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Basal ganglia dysfunction
  • Chronic motor tic disorder
  • Deep brain stimulation
  • Dystonia
  • Essential tremor
  • Movement – uncontrollable
  • Movement – uncontrolled or slow
  • Movement – uncoordinated
  • Movement – unpredictable or jerky
  • Obsessive-compulsive disorder
  • Parkinson disease
  • Progressive supranuclear palsy
  • Tourette syndrome
  • Tremor

Research Profile

Areas of Interest
  • Alzheimer’s Disease
  • Deep brain stimulation
  • Depression
  • Dystonia
  • ECT Refractory Depression
  • Medication Refractory Obsessive Compulsive Disorder
  • Multiple Sclerosis Tremor
  • Multiple System Atrophy (MSA)
  • Parkinson’s disease
  • Progressive Supranuclear Palsy (PSP)
  • Surgical Treatments for Movement Disorders
  • Surgical Treatments for Neuro-psychiatric Disorders
  • Tourette Syndrome

Publications

2020 Parkinsonism & Related Disorders
2020 Jama-Journal of the American Medical Association
2020 Parkinsonism & Related Disorders
2018 Journal of Parkinson's disease (Online)
2016 Journal of Neuropsychiatry and Clinical Neurosciences
2015 Translational Neurodegeneration
2015 Journal of Clinical and Experimental Neuropsychology
2014 Archives of Physical Medicine and Rehabilitation
2014 Current Opinion in Neurology
2014 Journal of Obsessive-Compulsive and Related Disorders
2013 Current Treatment Options in Neurology
2013 New England Journal of Medicine
2012 New England Journal of Medicine
2012 Journal of Geriatric Psychiatry and Neurology
2012 Journal of Neuropsychiatry and Clinical Neurosciences
2011 Parkinsonism & Related Disorders
2011 Journal of the International Neuropsychological Society
2011 Journal of the International Neuropsychological Society
2011 Journal of Neuropathology and Experimental Neurology
2010 Parkinsonism & Related Disorders
2010 Journal of Neurosurgery-Spine
2009 Parkinsonism & Related Disorders
2009 Stereotactic and Functional Neurosurgery
2009 International Journal of Neuroscience
2009 Journal of the Neurological Sciences
2009 Journal of Neurology Neurosurgery and Psychiatry
2008 Nature Clinical Practice Neurology
2008 Journal of Neurology Neurosurgery and Psychiatry
2004 American Journal of Ophthalmology
2004 Journal of Neurology Neurosurgery and Psychiatry
2003 Journal of Neurology Neurosurgery and Psychiatry

Grants

Aug 2020 ACTIVE
Interdisciplinary Training in Movement Disorders and Neurorestoration
NATL INST OF HLTH NINDS ·
May 2020 ACTIVE
Wearable-Sensor Driven Responsive Deep Brain Stimulation for the Improved Treatment of Essential Tremor
NATL INST OF HLTH NINDS ·
Jan 2020 ACTIVE
Application of Free-water Imaging & a Transcallosal Tractography Template in DLB: A Novel Biomarker
UF FOU · Mentor
Dec 2019 ACTIVE
LRRK2-Synuclein Interactions with Gut Inflammation in PD Pathogenesis
PARKINSONS FOU ·
Sep 2019 ACTIVE
Dual Lead Thalamic DBR-DBS Interface for Closed Loop Control of Severe Essential Tremor
NATL INST OF HLTH NINDS ·
Sep 2019 ACTIVE
Adoptive Cell Therapies and Translational Neuroimaging in Synucleinopathy: Implications for Dementia with Lewy Body and Parkinson's Disease
NATL INST OF HLTH NINDS ·
Aug 2019 – Apr 2020
Gait as a biomarker for clinicians and researchers in Parkinsons disease
TEL AVIV SOURASKY MEDICAL CENTER · Project Manager
Jul 2019 ACTIVE
University of Florida R25 Early Research Program for Neurology and Neurosurgery Residents
NATL INST OF HLTH NINDS · Principal Investigator
Jun 2019 ACTIVE
Improving Access to Deep Brain Stimulation Therapy
TOURETTE ASSOCIATION OF AMERICA · Principal Investigator
May 2019 ACTIVE
Local field potentials reveal reward processing and impulse control disorders in Parkinsons disease
NATL INST OF HLTH NINDS · Mentor
Mar 2019 ACTIVE
Ataxia Research Fund: Support for Ataxia research and education
UF FOU · Project Manager
Jul 2018 – Jun 2020
Physiologic Approach to Human Tics Tic Detector
AMER ACAD OF NEUROLOGY · Mentor
Apr 2018 – Jan 2020
CODY: Assistive Technology for SAH Assessments
US DEPT OF VETERANS AFFAIRS ·
Apr 2018 ACTIVE
Supraspinal Control of Human Locomotor Adaptation
NATL INST OF HLTH NINDS ·
Oct 2017 ACTIVE
Automated Analysis of Movement Disorders from Diffusion and Functional MRI
NATL SCIENCE FOU ·
Sep 2017 ACTIVE
Neuroethics of aDBS Systems Targeting Neuropsychiatric and Movement Disorders
BAYLOR UNIV COLLEGE OF MEDICINE · Principal Investigator
Sep 2017 ACTIVE
New Statistical and Computing Technologies for Bereaking the Barrier to Medical Data Sharing
NATL INST OF HLTH NIGMS ·
Sep 2017 ACTIVE
Neuroimaging Biomarkers in Parkinsonism: Differentiating Subtypes and Tracking Disease Progression
NATL INST OF HLTH NINDS ·
Aug 2017 ACTIVE
Mechanisms of airway protection dysfunction in Parkinson's disease
NATL INST OF HLTH NICHD ·
Sep 2016 ACTIVE
Closing the Loop on Tremor: A Responsive Deep Brain Stimulator for the Treatment of Essential Tremor
NATL INST OF HLTH NINDS ·
Aug 2016 ACTIVE
Scaling and Sequencing Motor Output in Humans: fMRI Study
NATL INST OF HLTH NINDS ·
Jul 2016 ACTIVE
The Human Thalamocortical Network in tourette syndrome
NATL INST OF HLTH NINDS · Principal Investigator
Jul 2016 – Jun 2020
Novel Management of Airway Protection in Parkinson's disease: A clinical trial
COLUMBIA UNIVERSITY · Project Manager
Jul 2015 ACTIVE
Cortex and Cerbellum in Visually-Guided Motor Behavior
NATL INST OF HLTH NINDS · Project Manager
Jul 2015 – Jun 2016
DBS for the Treatment of Dystonia
DYSTONIA MEDICAL RES FOU · Principal Investigator
Apr 2015 – Jan 2018
Study of TOPS DBS for the treatment of Parkinson?s dise
DEEP BRAIN INNOVATIONS LLC · Principal Investigator
Apr 2015 – Mar 2018
Airway protection deficits according to stimulus type in
NATL INST OF HLTH NIDCD · Project Manager
Feb 2015 ACTIVE
Mobile Decision Support System for Nurse Management of Neuromodulation Therapy
UNIV OF UTAH · Principal Investigator
Jan 2015 – Jul 2017
PD Closed Loop
FOX FOU, MICHAEL J · Principal Investigator
Jan 2015 – Dec 2017
A Responsive Closed-Loop Approach to Treat Freezing of Gait in Parkinsons Disease
UF FOU · Principal Investigator
Nov 2014 – Oct 2018
TSA CoE
TOURETTE ASSOCIATION OF AMERICA · Project Manager
Aug 2014 – Jul 2017
EnVivo 025-AD
INVENTIV HEALTH CLINICAL LLC · Principal Investigator
Mar 2014 – Dec 2017
Direct Functional Imaging of Electrical Brain Stimulation
ARIZONA STATE UNIVERSITY · Project Manager
Sep 2013 – Dec 2020
Implantable Neurostimulator for the Treatment of Parkinson's Disease.
BOSTON SCIENTIFIC CORP · Principal Investigator
Sep 2013 – Aug 2019
White Matter Connectivity and PD Cognitive Phenotypes
NATL INST OF HLTH NINDS · Project Manager
Jul 2013 ACTIVE
The Bachmann-Strauss Dystonia & Parkinson's Disease COE
UF FOU · Principal Investigator
Jul 2013 – Jul 2016
The Bachmann-Strauss Dystonia & Parkinson's Disease COE
BACHMANN-STRAUSS DYSTONIA & PARKINSON FO · Principal Investigator
Nov 2012 – Jun 2019
TSA INTERNATIONAL DATABASE OF DBS IN TS
TOURETTE ASSOCIATION OF AMERICA · Principal Investigator
Oct 2012 – Apr 2017
Dance for Life
PARKINSONS FOU · Project Manager
Sep 2012 – Sep 2018
Non-Invasive Markers of Neurodegeneration in Movement Di
NATL INST OF HLTH NINDS · Project Manager
Aug 2012 – Nov 2017
Advance Study
FUNCTIONAL NEUROMODULATION · Principal Investigator
Nov 2011 – Jul 2016
Scaling and Sequencing Motor Output in Humans: fMRI Stud
NATL INST OF HLTH NINDS · Project Manager
Jul 2011 – Sep 2019
Brain Bank for subjects implanted with the Libra Deep Brain Stimulation System
ST JUDE MEDICAL CENTER · Principal Investigator
Nov 2010 – Dec 2016
Ampicillin for DYT-1 Dystonia: a Pilot Trial for Safety
TYLER'S HOPE FOR A DYSTONIA CURE · Principal Investigator
Sep 2010 – Dec 2017
LTFU ET
ADVANCED NEUROMODULATION SYSTEMS · Principal Investigator
Jun 2010 – Jun 2019
Quality Improvement Initiative (QII) Phase II
PARKINSONS FOU · Project Manager
Mar 2010 – Mar 2016
Quantifying Deficits in Patients with Movement Disorders
UF FOU · Principal Investigator
Jul 2007 – Aug 2016
CTSI
UF RESEARCH FOU · Project Manager
Aug 2005 – Jul 2020
Ask The Doctor
PARKINSONS FOU · Principal Investigator

Patents

Published July 2008
Image Guidance System For Deep Brain Stimulation
#US 2009-0220136 A1
Issued October 2012
Multiple Lead Method for Deep Brain Stimulation
#8,295,935
Issued April 2017
Apparatuses and Methods for Securing Deep Brain Stimulation Leads
#9,610,437
Issued December 2017
Apparatuses and Methods for Securing Deep Brain Stimulation Leads (CON of 13879)
#9,833,612

Education

Fellow in Movement Disorders and Sterotactic Surgery for Movement Disorders
2000-2002 · Emory University
Residency – Neurology
2000 · University of Florida
Residency – Internal Medicine
1997 · University of Florida
Medical Degree
1996 · University of Florida

Contact Details

Phones:
Business:
(352) 294-5400
Emails: