Michael S Okun

Michael S Okun MD

Chair And Professor Of Neurology

Department: MD-NEUROLOGY-ADMIN/EDUC
Business Phone: (352) 294-5400
Business Email: okun@neurology.ufl.edu

About Michael S Okun

Michael S. Okun received his M.D. with honors from the University of Florida. He was fellowship trained by Mahlon DeLong, Jerrold Vitek and Ray Watts at Emory University in Atlanta GA before moving to found the movement disorders program at the University of Florida. He is currently Chair of Neurology, Professor and Executive Director of the Norman Fixel Institute for Neurological Diseases at the University of Florida Health College of Medicine. The UF institute he co-founded with Kelly D. Foote, M.D. is unique in that it is comprised of over 100 interdisciplinary faculty members from diverse areas of campus, all of whom are dedicated to care, outreach, education and research. Dr. Okun was instrumental in the construction of a one-stop patient-centered clinical-research experience for national and international patients seeking care at the University of Florida. This change in care and research delivery has since been named the service and science hub model of care. The UF based center draws national and international visitors interested in deploying this innovative clinical-research model. Dr. Okun has served as the National Medical Director for the Parkinson’s Foundation since 2006 and as the Medical Advisor for Tyler’s Hope for a Dystonia Cure. He has been supported by grants from the National Institutes of Health, the Smallwood Foundation, the Tourette Association of America, the Parkinson Alliance, the Bachmann-Strauss Foundation, the Parkinson’s Foundation, and the Michael J. Fox Foundation. Dr. Okun has an active research career exploring non-motor basal ganglia brain features and currently holds two NIH R01 grants and several foundation grants exploring various aspects of deep brain stimulation and neuromodulation. Dr. Okun has been an integral part of some of the pioneering studies exploring the cognitive, behavioral, and mood effects of brain stimulation and since 2005 his laboratory has been working to uncover the electrical brain signals associated with human tic. He has also partnered with Dr. Ayse Gunduz and Kelly Foote to develop a first generation of closed loop adaptive deep brain stimulation approaches. Dr. Okun was the founding PI for the International Database and Public Registry for Tourette Deep Brain Stimulation. He and his group have contributed data to support the FDA approval of several device related approaches now used to treat human disease. Dr. Okun holds the Adelaide Lackner Professorship in Neurology and has published over 400 peer-reviewed articles. He is a poet (Lessons From the Bedside, 1995) and his book, Parkinson’s Treatment: 10 Secrets to a Happier Life, was translated into over 20 languages. Dr. Okun was recognized in a 2015 White House ceremony by the Obama administration as a Champion of Change for Parkinson’s Disease.

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Basal ganglia dysfunction
  • Chronic motor tic disorder
  • Deep brain stimulation
  • Dystonia
  • Essential tremor
  • Movement – uncontrollable
  • Movement – uncontrolled or slow
  • Movement – uncoordinated
  • Movement – unpredictable or jerky
  • Obsessive-compulsive disorder
  • Parkinson disease
  • Progressive supranuclear palsy
  • Tourette syndrome
  • Tremor

Research Profile

Areas of Interest
  • Deep brain stimulation
  • Depression
  • Dystonia
  • Multiple Sclerosis Tremor
  • Parkinson’s disease
  • Progressive Supranuclear Palsy (PSP)
  • Surgical Treatments for Movement Disorders
  • Surgical Treatments for Neuro-psychiatric Disorders
  • Tourette Syndrome
  • Multiple System Atrophy (MSA)
  • Medication Refractory Obsessive Compulsive Disorder
  • Alzheimer’s Disease
  • ECT Refractory Depression

Publications

2018 Movement disorders : official journal of the Movement Disorder Society
2016 Journal of Neuropsychiatry and Clinical Neurosciences
2015 Journal of Clinical and Experimental Neuropsychology
2014 Current Opinion in Neurology
2014 Journal of Obsessive-Compulsive and Related Disorders
2014 Archives of Physical Medicine and Rehabilitation
2013 Current Treatment Options in Neurology
2013 New England Journal of Medicine
2012 New England Journal of Medicine
2012 Journal of Geriatric Psychiatry and Neurology
2012 Journal of Neuropsychiatry and Clinical Neurosciences
2011 Parkinsonism & Related Disorders
2011 Journal of the International Neuropsychological Society
2011 Journal of the International Neuropsychological Society
2010 Parkinsonism & Related Disorders
2010 Parkinsonism & Related Disorders
2010 Journal of Neurosurgery-Spine
2009 Journal of the Neurological Sciences
2009 Stereotactic and Functional Neurosurgery
2009 Parkinsonism & Related Disorders
2009 Journal of the Neurological Sciences
2009 Journal of Neurology Neurosurgery and Psychiatry
2009 Stereotactic and Functional Neurosurgery
2009 International Journal of Neuroscience
2008 Nature Clinical Practice Neurology
2008 Journal of Neurology Neurosurgery and Psychiatry
2004 Journal of Neurology Neurosurgery and Psychiatry
2003 Frontiers in Bioscience-Landmark
2003 Journal of Neurology Neurosurgery and Psychiatry

Grants

July 2019ACTIVE
University of Florida R25 Early Research Program for Neurology and Neurosurgery Residents
NATL INST OF HLTH NINDS · Principal Investigator
June 2019ACTIVE
Improving Access to Deep Brain Stimulation Therapy
TOURETTE ASSOCIATION OF AMERICA · Principal Investigator
May 2019ACTIVE
Local field potentials reveal reward processing and impulse control disorders in Parkinsons disease
NATL INST OF HLTH NINDS ·
March 2019ACTIVE
Ataxia Research Fund: Support for Ataxia research and education
UF FOU · Project Manager
April 2018ACTIVE
CODY: Assistive Technology for SAH Assessments
US DEPT OF VETERANS AFFAIRS ·
April 2018ACTIVE
Supraspinal Control of Human Locomotor Adaptation
NATL INST OF HLTH NINDS ·
October 2017ACTIVE
Automated Analysis of Movement Disorders from Diffusion and Functional MRI
NATL SCIENCE FOU · Project Manager
September 2017ACTIVE
New Statistical and Computing Technologies for Bereaking the Barrier to Medical Data Sharing
NATL INST OF HLTH NIGMS · Project Manager
September 2017ACTIVE
Neuroethics of aDBS Systems Targeting Neuropsychiatric and Movement Disorders
BAYLOR UNIV COLLEGE OF MEDICINE · Principal Investigator
September 2017ACTIVE
Neuroimaging Biomarkers in Parkinsonism: Differentiating Subtypes and Tracking Disease Progression
NATL INST OF HLTH NINDS ·
August 2017ACTIVE
Mechanisms of airway protection dysfunction in Parkinson's disease
NATL INST OF HLTH NICHD · Project Manager
September 2016ACTIVE
Closing the Loop on Tremor: A Responsive Deep Brain Stimulator for the Treatment of Essential Tremor
NATL INST OF HLTH NINDS ·
August 2016ACTIVE
Scaling and Sequencing Motor Output in Humans: fMRI Study
NATL INST OF HLTH NINDS ·
July 2016ACTIVE
Novel Management of Airway Protection in Parkinson's disease: A clinical trial
COLUMBIA UNIVERSITY · Project Manager
July 2016ACTIVE
The Human Thalamocortical Network in tourette syndrome
NATL INST OF HLTH NINDS · Principal Investigator
July 2015ACTIVE
Cortex and Cerbellum in Visually-Guided Motor Behavior
NATL INST OF HLTH NINDS · Project Manager
July 2015 – June 2016
DBS for the Treatment of Dystonia
DYSTONIA MEDICAL RES FOU · Principal Investigator
April 2015 – January 2018
Study of TOPS DBS for the treatment of Parkinson?s dise
DEEP BRAIN INNOVATIONS LLC · Principal Investigator
April 2015 – March 2018
Airway protection deficits according to stimulus type in
NATL INST OF HLTH NIDCD · Project Manager
February 2015ACTIVE
Mobile Decision Support System for Nurse Management of Neuromodulation Therapy
UNIV OF UTAH · Principal Investigator
January 2015 – July 2017
PD Closed Loop
FOX FOU, MICHAEL J · Principal Investigator
January 2015 – December 2017
A Responsive Closed-Loop Approach to Treat Freezing of Gait in Parkinsons Disease
UF FOU · Principal Investigator
November 2014 – October 2018
TSA CoE
TOURETTE ASSOCIATION OF AMERICA · Project Manager
August 2014 – July 2017
EnVivo 025-AD
INVENTIV HEALTH CLINICAL LLC · Principal Investigator
March 2014 – December 2017
Direct Functional Imaging of Electrical Brain Stimulation
ARIZONA STATE UNIVERSITY · Project Manager
September 2013 – December 2020
Implantable Neurostimulator for the Treatment of Parkinson's Disease.
BOSTON SCIENTIFIC CORP · Principal Investigator
September 2013 – August 2019
White Matter Connectivity and PD Cognitive Phenotypes
NATL INST OF HLTH NINDS · Project Manager
July 2013 – July 2016
The Bachmann-Strauss Dystonia & Parkinson's Disease COE
UF FOU · Principal Investigator
July 2013 – July 2016
The Bachmann-Strauss Dystonia & Parkinson's Disease COE
BACHMANN-STRAUSS DYSTONIA & PARKINSON FO · Principal Investigator
November 2012 – June 2019
TSA INTERNATIONAL DATABASE OF DBS IN TS
TOURETTE ASSOCIATION OF AMERICA · Principal Investigator
October 2012 – April 2017
Dance for Life
PARKINSONS FOU · Project Manager
September 2012 – September 2018
Non-Invasive Markers of Neurodegeneration in Movement Di
NATL INST OF HLTH NINDS · Project Manager
August 2012 – November 2017
Advance Study
FUNCTIONAL NEUROMODULATION · Principal Investigator
November 2011 – July 2016
Scaling and Sequencing Motor Output in Humans: fMRI Stud
NATL INST OF HLTH NINDS · Project Manager
July 2011 – September 2019
ANS Brain Bank
ST JUDE MEDICAL CENTER · Principal Investigator
November 2010 – December 2016
Ampicillin for DYT-1 Dystonia: a Pilot Trial for Safety
TYLER'S HOPE FOR A DYSTONIA CURE · Principal Investigator
September 2010 – December 2017
A Long-Term Follow Up Study of the Patients Who Underwent Unilateral or Bilateral Stimulation of the (VIM) Using the Libra Deep Brain Stimulation System for the Suppression of Tremor in the Upper Extremities of Patients with Essential Tremor
ADVANCED NEUROMODULATION SYSTEMS · Principal Investigator
June 2010 – June 2019
Quality Improvement Initiative (QII) Phase II
PARKINSONS FOU · Project Manager
March 2010 – March 2016
Quantifying Deficits in Patients with Movement Disorders
UF FOU · Principal Investigator
July 2007 – August 2016
CTSI
UF RESEARCH FOU · Project Manager
August 2005ACTIVE
Ask The Doctor
PARKINSONS FOU · Principal Investigator

Patents

Issued December 2017
Apparatuses and Methods for Securing Deep Brain Stimulation Leads (CON of 13879)
9,833,612
Issued April 2017
Apparatuses and Methods for Securing Deep Brain Stimulation Leads
9,610,437
Issued October 2012
Multiple Lead Method for Deep Brain Stimulation
8,295,935
Published July 2008
Image Guidance System For Deep Brain Stimulation
US 2009-0220136 A1

Education

2000-2002
Fellow in Movement Disorders and Sterotactic Surgery for Movement Disorders
Emory University
2000
Residency – Neurology
University of Florida
1997
Residency – Internal Medicine
University of Florida
1996
Medical Degree
University of Florida