Michael A Pizzi, DO, PhD, FCCM
Associate Professor Departments Of Neurology And Neurosurgery, Division Of Neurocritical Care; Affiliate Clinical Associate Professor Department Of Neuroscience
Department:
MD-NEURO-NEUROCRITICAL CARE
Business Phone:
(352) 273-9000
Business Email:
mpizzi@ufl.edu
About Michael A Pizzi
Michael Pizzi, DO, PhD, FCCM is a board-certified neurologist and neurointensivist. He received his medical degree from Chicago College of Osteopathic Medicine. During medical school Dr. Pizzi was selected for a clinical and research externship at the Rehabilitation Institute of Chicago, where his work on using nanoparticles to facilitate axonal regeneration won the Sarah Baskin award for best research project. Dr. Pizzi completed his internship in internal medicine and neurology residency at the University of Florida-Jacksonville, where he served as chief administrative resident. Dr. Pizzi completed his neurocritical care fellowship at Mayo Clinic Florida, where he received the critical care echocardiography fellow of the year award.
Prior to medical school, Dr. Pizzi earned his MS (Florida State University) and PhD (Medical College of Wisconsin) in neuroscience. Dr. Pizzi’s dissertation research project utilized a novel mechanism by which cancer cells spread in order to facilitate axonal regeneration after traumatic spinal cord injury.
Dr. Pizzi serves on various departmental committees (Co-Chair, Faculty Search Committee, member of Clinical Competency Committee), College of Medicine committee (Therapeutic Temperature Management Committee), and University committee (Chair, Osmotherapy Task Force). He also serves outside the University of Florida as a member of the Society of Critical Care Medicine Scientific Review committee, and member of the editorial board of Critical Care Explorations. He is the co-founder and course director of the Mayo Clinic Neuroscience Convergence meeting, and course director for the Mayo Clinic Neurocritical Care Review Course.
Outside the hospital and lab, he enjoys spending time with his family, scuba diving, and kayaking.
Accomplishments
Fellow of Critical Care Medicine
2024
·
American College of Critical Care Medicine
Exemplary Teacher
2022
·
UF College of Medicine
In Vivo Measurements of Blood-Brain Barrier Permeability in a Mouse Model of Traumatic Brain Injury
2022
·
UF BRAIN Center Neural Injury Award
Chair, Osmotherapy Task Force
2021
·
University of Florida
Co-Chair Faculty Search Committee
2021
·
Department of Neurology, University of Florida
Course Director, Deeper Dive in Basic Sciences (DIBS) Seminar
2021
·
University of Florida
Member, Therapeutic Temperature Management Committee
2021
·
University of Florida
Training in 2-photon Microscopy of Mouse Cerebrovasculature
2021
·
University of Florida Faculty Enhancement Opportunity Grant
Conducted experiments to Stabilize the blood-brain barrier after acute ischemic stroke
2020
·
University of Florida
Member, Clinical Competency Committee
2020
·
Department of Neurology, University of Florida
Exemplary Teacher
2018
·
UF College of Medicine
Faculty Golden Apple Award
2018
·
Department of Neurology at UF-Jacksonville
Critical Care Echocardiography Fellow of the Year
2017
·
Mayo Clinic
Sarah Baskin Award for Excellence in Research
2008
·
Department of Physical Medicine and Rehabilitation, Northwestern University
Student Travel Award
2004
·
National Neurotrauma Society
Teaching Profile
Courses Taught
2021
MDC7800 Neurology Clerkship
Board Certifications
-
Neurocritical CareUnited Council for Neurologic Subspecialties
-
NeurologyAmerican Board of Psychiatry and Neurology
Clinical Profile
Specialties
- Neurocritical Care
Areas of Interest
- Acute Ischemic Stroke
- Traumatic Brain Injury
Research Profile
Preserving the blood-brain barrier after acute brain injury; Characterize the role of the endothelial glycocalyx in regulating cerebral blood flow; Investigating the effects of ketone esters on cerebral blood flow; Developing models to measure brain compliance.
Open Researcher and Contributor ID (ORCID)
0000-0003-0192-4371
Publications
2024
Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries in mice.
NeuroImage.
298
[DOI] 10.1016/j.neuroimage.2024.120764.
[PMID] 39089604.
2024
Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2024.01.25.577316.
[PMID] 38328104.
2024
Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[DOI] 10.1177/0271678X241270452.
[PMID] 39113406.
2024
Procalcitonin As Diagnostic Tool for CNS Infections-Overall, Not Good Enough (Yet?).
Critical care medicine.
52(1):163-165
[DOI] 10.1097/CCM.0000000000006075.
[PMID] 38095527.
2023
Outcomes in Patients With COVID-19 With Acute Encephalopathy and Coma: An International Prospective Study.
Neurology.
100(22):e2247-e2258
[DOI] 10.1212/WNL.0000000000207263.
[PMID] 37041081.
2022
5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report.
The Neurohospitalist.
12(2):366-370
[DOI] 10.1177/19418744211068913.
[PMID] 35419161.
2022
Catch Me If You Can-How Herpes Simplex Virus Tries to Evade Diagnosis in Viral Encephalitis.
Critical care medicine.
50(7):1170-1173
[DOI] 10.1097/CCM.0000000000005501.
[PMID] 35726985.
2022
Clinical Challenges of Acute Porphyria in the Young Adult.
The Neurohospitalist.
12(2):377-382
[DOI] 10.1177/19418744211073029.
[PMID] 35419127.
2022
Effect of desmopressin acetate on acute spontaneous intracranial hemorrhage in patients on antiplatelet therapy.
Journal of the neurological sciences.
434
[DOI] 10.1016/j.jns.2022.120142.
[PMID] 35081458.
2022
Pregabalin for Recurrent Seizures in Critical Illness: A Promising Adjunctive Therapy, Especially for cyclic Seizures.
Neurocritical care.
37(1):140-148
[DOI] 10.1007/s12028-022-01459-6.
[PMID] 35217998.
2021
Acute Neurologic Manifestations of Respiratory Viruses.
Continuum (Minneapolis, Minn.).
27(5):1365-1381
[DOI] 10.1212/CON.0000000000001007.
[PMID] 34618764.
2021
Pterygopalatine Fossa Blockade as Novel, Narcotic-Sparing Treatment for Headache in Patients with Spontaneous Subarachnoid Hemorrhage.
Neurocritical care.
35(1):241-248
[DOI] 10.1007/s12028-020-01157-1.
[PMID] 33403584.
2021
The Modified Early Warning Score: A Useful Marker of Neurological Worsening but Unreliable Predictor of Sepsis in the Neurocritically Ill-A Retrospective Cohort Study.
Critical care explorations.
3(5)
[DOI] 10.1097/CCE.0000000000000386.
[PMID] 34036267.
2021
Ultrasound of Optic Nerve Sheath Diameter and Stroke Outcomes.
Critical care explorations.
3(11)
[DOI] 10.1097/CCE.0000000000000565.
[PMID] 34841250.
2020
Factor Xa Inhibitor-Related Intracranial Hemorrhage: Results From a Multicenter, Observational Cohort Receiving Prothrombin Complex Concentrates.
Circulation.
141(21):1681-1689
[DOI] 10.1161/CIRCULATIONAHA.120.045769.
[PMID] 32264698.
2020
Intracranial Pressure, More Than a Number?
Critical care medicine.
48(12):e1365-e1366
[DOI] 10.1097/CCM.0000000000004565.
[PMID] 33255132.
2019
Adult Presentation of Ornithine Transcarbamylase Deficiency: 2 Illustrative Cases of Phenotypic Variability and Literature Review.
The Neurohospitalist.
9(1):30-36
[DOI] 10.1177/1941874418764817.
[PMID] 30671162.
2019
De novo temporal intermittent rhythmic delta activity after laser interstitial thermal therapy for mesial temporal lobe epilepsy predicts poor seizure outcome.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
130(1):122-127
[DOI] 10.1016/j.clinph.2018.11.012.
[PMID] 30529878.
2019
Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis.
Neurology.
92(18):e2150-e2164
[DOI] 10.1212/WNL.0000000000007397.
[PMID] 30952792.
2018
Investigational drugs for vasospasm after subarachnoid hemorrhage.
Expert opinion on investigational drugs.
27(4):313-324
[DOI] 10.1080/13543784.2018.1460353.
[PMID] 29600883.
2018
Post-Intensive Care Unit Cognitive Dysfunction
.
69(1):24-28
2017
A Preliminary Observational Study of Anovulatory Uterine Bleeding After Aneurysmal Subarachnoid Hemorrhage.
The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses.
49(6):363-371
[DOI] 10.1097/JNN.0000000000000318.
[PMID] 29117032.
2017
Ambulance-based assessment of NIH Stroke Scale with telemedicine: A feasibility pilot study.
Journal of telemedicine and telecare.
23(4):476-483
[DOI] 10.1177/1357633X16648490.
[PMID] 27177870.
2017
Neurologic Complications of Solid Organ Transplantation.
Neurologic clinics.
35(4):809-823
[DOI] 10.1016/j.ncl.2017.06.013.
[PMID] 28962815.
2017
Stroke Diagnosis and Treatment in the Emergency Department.
JAMA neurology.
74(3)
[DOI] 10.1001/jamaneurol.2016.5561.
[PMID] 28114682.
2017
Transition from intravenous to enteral ketamine for treatment of nonconvulsive status epilepticus.
Journal of intensive care.
5
[DOI] 10.1186/s40560-017-0248-6.
[PMID] 28808577.
2017
Update on Neurocritical Care of Stroke.
Current cardiology reports.
19(8)
[DOI] 10.1007/s11886-017-0881-7.
[PMID] 28646445.
2016
Cerebral Venous Thrombosis Associated with Intracranial Hemorrhage and Timing of Anticoagulation after Hemicraniectomy.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
25(9):2312-6
[DOI] 10.1016/j.jstrokecerebrovasdis.2016.05.025.
[PMID] 27321968.
2016
Precision medicine of aneurysmal subarachnoid hemorrhage, vasospasm and delayed cerebral ischemia.
Expert review of neurotherapeutics.
16(11):1251-1262
[PMID] 27314601.
2015
Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory.
PloS one.
10(6)
[DOI] 10.1371/journal.pone.0131266.
[PMID] 26098332.
2014
The societal integration of individuals with epilepsy: perspectives for the 21st century.
Epilepsy & behavior : E&B.
35:42-9
[DOI] 10.1016/j.yebeh.2014.04.006.
[PMID] 24798409.
2007
Matrix metalloproteinases and proteoglycans in axonal regeneration.
Experimental neurology.
204(2):496-511
[PMID] 17254568.
2006
Pain with no gain: allodynia following neural stem cell transplantation in spinal cord injury.
Experimental neurology.
201(2):335-48
[PMID] 16839548.
2006
Transplantation of fibroblasts that overexpress matrix metalloproteinase-3 into the site of spinal cord injury in rats.
Journal of neurotrauma.
23(12):1750-65
[PMID] 17184186.
2004
Characterization of a chondroitin sultate proteoglycan associated with regeneration in goldfish optic tract.
Neurochemical research.
29(4):719-28
[PMID] 15098933.
Grants
Jul 2006
ACTIVE
BRAIN AND SPINAL CORD INJURY RESEARCH
Role: Project Manager
Funding: FL DEPT OF HLTH
Education
Fellowship- Neurocritical Care
2017
·
Mayo Clinic
Residency – Neurology
2015
·
University of Florida – Jacksonville
Internship – Internal Medicine
2012
·
University of Florida – Jacksonville
DO
2011
·
Midwestern University
PhD Neuroscience
2006
·
Medical College of Wisconsin
MS Neuroscience
2001
·
Florida State University
BS Biology
1994
·
Northern Illinois University
Contact Details
Phones:
- Business:
- (352) 273-9000
Emails:
- Business:
- mpizzi@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100265
GAINESVILLE FL 32610 - Business Street:
-
1149 NEWELL DR RM L3 100
GAINESVILLE FL 32610