William Roth

William Roth, MD

Assistant Professor Of Neurology And Neurosurgery, Division Of Neurocritical Care

Department: MD-NEURO-NEUROCRITICAL CARE
Business Phone: (352) 273-5550

About William Roth

William H. Roth, MD is a clinical assistant professor with the Department of Neurology at the University of Florida College of Medicine. Dr. Roth is board-certified in neurology by the American Board of Psychiatry and Neurology.

Dr. Roth graduated with medical degree as the valedictorian at Chicago Medical School at Rosalind Franklin University in North Chicago, IL. After his internal medicine residency at University of Chicago affiliate NorthShore University Health System, he completed his neurology residency at the Neurological Institute of New York at Columbia University Irving Medical Center, followed by an additional year as chief resident. He then completed his neurocritical care fellowship at New York Presbyterian Hospital – Columbia University and Weill Cornell University Medical Centers.

During his training, he served on various hospital committees, received multiple awards and contributed to numerous research publications. His current research focuses on the role of the gut microbiome in neuroinflammation and secondary brain injury and is the principal investigator of the Gut Microbiome in Acute Brain Injury (GUT-ABI) project. In addition, he serves as the site principal investigator for the multicenter RAISE trial and serves as co-project leader with Dr. Michael Pizzi for the UF Neuro ICU SickBay initiative focused on physiological data monitoring in the neurocritically ill. He is currently a member of the American Heart Association, American Academy of Neurology, Society of Critical Care Medicine, and the Neurocritical Care Society.

In his free time, he enjoys cheering on his hometown Chicago Cubs, playing guitar and enjoying craft cocktails with his wife.

Accomplishments

Enhanced Adult Leadership Program Recipient
2017 · American Academy of Neurology
Scholarship Award, Highest Average – Clinical Sciences
2013 · Chicago Medical School
Scholastic Achievement Award
2013 · Chicago Medical School Alumni Association

Board Certifications

  • Neurology
    American Board of Psychiatry and Neurology

Clinical Profile

Specialties
  • Neurology
Subspecialties
  • Neurocritical Care
Areas of Interest
  • Spinal cord trauma
  • Spinal injury
  • Stroke
  • Traumatic Brain Injury

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-2451-9221

Areas of Interest
  • Aging
  • Gut-brain homeostasis
  • Hemorrhage
  • Neurological recovery patterns

Publications

2021
COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital.
Brain : a journal of neurology. [DOI] 10.1093/brain/awab148. [PMID] 33856027.
2021
The Modified Early Warning Score: A Useful Marker of Neurological Worsening but Unreliable Predictor of Sepsis in the Neurocritically Ill-A Retrospective Cohort Study.
Critical care explorations. 3(5) [DOI] 10.1097/CCE.0000000000000386. [PMID] 34036267.
2021
Tryptophan Metabolism and Gut-Brain Homeostasis
International Journal of Molecular Sciences. 22(6) [DOI] 10.3390/ijms22062973. [PMID] 33804088.
2021
Vitamin B12 and gut-brain homeostasis in the pathophysiology of ischemic stroke
EBioMedicine. 73 [DOI] 10.1016/j.ebiom.2021.103676. [PMID] 34749301.
2020
Gastrointestinal Disorders and Risk of First-Ever Ischemic Stroke.
Stroke. 51(12):3577-3583 [DOI] 10.1161/STROKEAHA.120.030643.
2020
Hematoma expansion is more frequent in deep than lobar intracerebral hemorrhage.
Neurology. 95(24):e3386-e3393 [DOI] 10.1212/WNL.0000000000010990.
2020
Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage.
Acta neuropathologica communications. 8(1) [DOI] 10.1186/s40478-020-01024-2. [PMID] 32847628.
2018
Cerebral Ischemic Reperfusion Injury Following Recanalization of Large Vessel Occlusions.
Neurosurgery. 82(6):781-789 [DOI] 10.1093/neuros/nyx341. [PMID] 28973661.
2018
Determinants of Long-Term Neurological Recovery Patterns Relative to Hospital Discharge Among Cardiac Arrest Survivors.
Critical care medicine. 46(2):e141-e150 [DOI] 10.1097/CCM.0000000000002846. [PMID] 29135522.
2018
Early myoclonus following anoxic brain injury.
Neurology. Clinical practice. 8(3):249-256 [DOI] 10.1212/CPJ.0000000000000466. [PMID] 30105165.
2017
Anchoring Pipeline Flow Diverter Construct in the Treatment of Traumatic Distal Cervical Carotid Artery Injury.
Interventional neurology. 6(3-4):153-162 [DOI] 10.1159/000457836. [PMID] 29118792.
2017
Encephalomyelitis Following Definitive Zika Virus Infection.
Neurology(R) neuroimmunology & neuroinflammation. 4(4) [DOI] 10.1212/NXI.0000000000000349. [PMID] 28508009.
2017
Histopathological Differences Between the Anterior and Posterior Brain Arteries as a Function of Aging.
Stroke. 48(3):638-644 [DOI] 10.1161/STROKEAHA.116.015630. [PMID] 28196941.
2016
Use of Intra-aortic- Balloon Pump Counterpulsation in Patients with Symptomatic Vasospasm Following Subarachnoid Hemorrhage and Neurogenic Stress Cardiomyopathy.
Journal of vascular and interventional neurology. 9(1):28-34 [PMID] 27403221.
2009
Alzheimer’s-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal.
Toxicology and applied pharmacology. 240(2):189-97 [DOI] 10.1016/j.taap.2009.07.018. [PMID] 19631677.

Grants

Dec 2021 ACTIVE
A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone in status epilepticus
Role: Principal Investigator
Funding: MARINUS PHARMACEUTICALS via BIOMEDICAL ADVANCED RES & DEVLPMT AUTHOR

Education

Fellow, Neurocritical Care
2018-2020 · Columbia University College of Physicians & Surgeons
Fellowship, Neurocritical Care
2018-2020 · New York-Presbyterian Hospital
Neurology Resident
2014-2017 · Columbia University College of Physicians & Surgeons
Residency, Neurology
2014-2017 · Columbia University Irving Medical Center
Intern – Internal Medicine
2013-2014 · University of Chicago (NorthShore University)
MD
2009-2013 · Chicago Medical School
Medical Degree
2009-2013 · Chicago Medical School at Rosalind Franklin University
Bachelor's Degree, Psychology
2004-2008 · University of Illinois at Urbana-Champaign
BS in Psychology
2004-2008 · University of Illinois at Urbana-Champaign

Contact Details

Phones:
Business:
(352) 273-5550
Emails:
Addresses:
Business Mailing:
PO Box 100236
GAINESVILLE FL 32610
Business Street:
1149 NEWELL DR RM L3 100
GAINESVILLE FL 32610