Hong Xing,
Assistant In
Department:
MD-NEUROLOGY-MOVEMENT DISORDER
Business Phone:
(352) 392-0670
Business Email:
hongxing@ufl.edu
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-9909-2333
Publications
Academic Articles
2023
Motor deficit and lack of overt dystonia in Dlx conditional Dyt1 knockout mice.
Behavioural brain research.
439
[DOI] 10.1016/j.bbr.2022.114221.
[PMID] 36417958.
2022
Electrophysiological characterization of the striatal cholinergic interneurons in Dyt1 ΔGAG knock-in mice.
Dystonia (Lausanne, Switzerland).
1
[DOI] 10.3389/dyst.2022.10557.
[PMID] 36329866.
2022
Further Studies on the Role of BTBD9 in the Cerebellum, Sleep-like Behaviors and the Restless Legs Syndrome.
Neuroscience.
505:78-90
[DOI] 10.1016/j.neuroscience.2022.10.008.
[PMID] 36244636.
2022
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice.
Molecular and cellular neurosciences.
121
[DOI] 10.1016/j.mcn.2022.103756.
[PMID] 35843530.
2022
Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins.
Marine drugs.
20(1)
[DOI] 10.3390/md20010049.
[PMID] 35049904.
2021
Alteration of the cholinergic system and motor deficits in cholinergic neuron-specific Dyt1 knockout mice.
Neurobiology of disease.
154
[DOI] 10.1016/j.nbd.2021.105342.
[PMID] 33757902.
2021
Characterization of the direct pathway in Dyt1 ΔGAG heterozygous knock-in mice and dopamine receptor 1-expressing-cell-specific Dyt1 conditional knockout mice.
Behavioural brain research.
411
[DOI] 10.1016/j.bbr.2021.113381.
[PMID] 34038798.
2021
Investigating the role of striatal dopamine receptor 2 in motor coordination and balance: Insights into the pathogenesis of DYT1 dystonia.
Behavioural brain research.
403
[DOI] 10.1016/j.bbr.2021.113137.
[PMID] 33476687.
2020
A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in Its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors.
Molecular pharmacology.
98(2):168-180
[DOI] 10.1124/mol.119.118786.
[PMID] 32474444.
2020
A Pharmacological Comparison of Two Isomeric Nicotinic Receptor Agonists: The Marine Toxin Isoanatabine and the Tobacco Alkaloid Anatabine.
Marine drugs.
18(2)
[DOI] 10.3390/md18020106.
[PMID] 32053997.
2020
BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome.
Brain structure & function.
225(6):1743-1760
[DOI] 10.1007/s00429-020-02090-x.
[PMID] 32468214.
2020
Decreased number of striatal cholinergic interneurons and motor deficits in dopamine receptor 2-expressing-cell-specific Dyt1 conditional knockout mice.
Neurobiology of disease.
134
[DOI] 10.1016/j.nbd.2019.104638.
[PMID] 31618684.
2020
Deficiency of Meis1, a transcriptional regulator, in mice and worms: Neurochemical and behavioral characterizations with implications in the restless legs syndrome.
Journal of neurochemistry.
155(5):522-537
[DOI] 10.1111/jnc.15177.
[PMID] 32910473.
2020
The abnormal firing of Purkinje cells in the knockin mouse model of DYT1 dystonia.
Brain research bulletin.
165:14-22
[DOI] 10.1016/j.brainresbull.2020.09.011.
[PMID] 32976982.
2020
The Role of BTBD9 in the Cerebellum, Sleep-like Behaviors and the Restless Legs Syndrome.
Neuroscience.
440:85-96
[DOI] 10.1016/j.neuroscience.2020.05.021.
[PMID] 32446853.
2020
The role of BTBD9 in the cerebral cortex and the pathogenesis of restless legs syndrome.
Experimental neurology.
323
[DOI] 10.1016/j.expneurol.2019.113111.
[PMID] 31715135.
2019
Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine.
Marine drugs.
17(11)
[DOI] 10.3390/md17110614.
[PMID] 31671780.
2019
The Role of BTBD9 in Striatum and Restless Legs Syndrome.
eNeuro.
6(5)
[DOI] 10.1523/ENEURO.0277-19.2019.
[PMID] 31444227.
2017
Comparison of tumor biology of two distinct cell sub-populations in lung cancer stem cells.
Oncotarget.
8(57):96852-96864
[DOI] 10.18632/oncotarget.18451.
[PMID] 29228576.
2015
Non-competitive Inhibition of Nicotinic Acetylcholine Receptors by Ladybird Beetle Alkaloids.
Neurochemical research.
40(10):2078-86
[DOI] 10.1007/s11064-014-1466-0.
[PMID] 25370792.
2013
APS8, a polymeric alkylpyridinium salt blocks α7 nAChR and induces apoptosis in non-small cell lung carcinoma.
Marine drugs.
11(7):2574-94
[DOI] 10.3390/md11072574.
[PMID] 23880932.
2009
Amyloid-beta induces a caspase-mediated cleavage of P2X4 to promote purinotoxicity.
Neuromolecular medicine.
11(2):63-75
[DOI] 10.1007/s12017-009-8073-2.
[PMID] 19562525.
2009
Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors.
British journal of pharmacology.
157(2):320-30
[DOI] 10.1111/j.1476-5381.2009.00156.x.
[PMID] 19338581.
2009
Lsoanatabine, a Naturally Occurring Alpha 4 Beta 2 Nicotinic Receptor Agonist
Biochemical Pharmacology.
78(7):906-907
[DOI] 10.1016/j.bcp.2009.06.047.
2008
TRPM8 mechanism of autonomic nerve response to cold in respiratory airway.
Molecular pain.
4
[DOI] 10.1186/1744-8069-4-22.
[PMID] 18534015.
2007
TRPM8 mechanism of cold allodynia after chronic nerve injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
27(50):13680-90
[PMID] 18077679.
2006
Chemical and cold sensitivity of two distinct populations of TRPM8-expressing somatosensory neurons.
Journal of neurophysiology.
95(2):1221-30
[PMID] 16424459.
2005
Substance P-driven feed-forward inhibitory activity in the mammalian spinal cord.
Molecular pain.
1
[PMID] 15987503.
2004
Menthol-induced Ca2+ release from presynaptic Ca2+ stores potentiates sensory synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
24(3):762-71
[PMID] 14736862.
Grants
Sep 2024
ACTIVE
Striatal Contribution to the Motor Symptoms and Aphasia in GRN-FTD
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Sep 2022
ACTIVE
Pathophysiology of DYT1 dystonia: Targeted Mouse Models
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Mar 2021
– Mar 2024
Novel Therapy Development for Dystonia
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION
Sep 2020
– Aug 2023
Characterization of Meis1 mutant mice and implications in restless legs syndrome and other sleep disorders
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Aug 2020
– Jul 2023
Characterization of the involvement of the cerebellum in animal models of C9orf72 ALS/FTD
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Jun 2018
– Dec 2021
Chemogenetic modulation of striatal cholinergic interneurons in DYT1 dystonia
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION
Contact Details
Phones:
- Business:
- (352) 392-0670
Emails:
- Business:
- hongxing@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100236
GAINESVILLE FL 32610