WHAT IS TUBEROUS SCLEROSIS COMPLEX? TSC
Tuberous sclerosis complex (TSC) is a genetic disorder that causes non-malignant tumors to form in many different organs, primarily in the brain, eyes, heart, kidney, skin and lungs. The aspects of TSC that most strongly impact quality of life are generally associated with the brain: seizures, developmental delay, intellectual disability and autism. However, many people with TSC are living independent, healthy lives and enjoying challenging professions such as doctors, lawyers, educators and researchers. The incidence and severity of the various aspects of TSC vary widely between individuals—even between identical twins. Seizures remain one of the most common neurological features of TSC, occurring in 85% of individuals with TSC; therefore, the early diagnosis and treatment of these seizures are critically important.
The UF Health Tuberous Sclerosis Center team sees pediatric and adult patients at the Tuberous Sclerosis Clinic at UF Health Medical Plaza and Neuro Medicine Hospital . This is one of few clinics in the State of Florida dedicated specifically to the care of individuals with tuberous sclerosis complex (TSC). The mission of the Tuberous Sclerosis Clinic is to provide multidisciplinary, comprehensive care of children and adults with TSC and to promote education and awareness about the disease. Because TSC often affects multiple organs throughout the body, the clinic incorporates a multidisciplinary approach involving physicians, nurses, therapists, and other staff members from different UF Health specialty divisions, including cardiology, dermatology, genetics, nephrology, neuropsychology, neurosurgery, ophthalmology, psychiatry, and urology.
Children are seen primarily at the TSC Clinic at 1549 Gale Lemerand Drive, Second Floor, Gainesville, FL and affiliated pediatric subspecialty clinics at UF Health Children’s Hospital.
The adult TSC Clinic site is located at the UF Health NeuroMedicine Hospital at 1505 SW Archer Road, Ground Floor, Gainesville, FL 32608.
Meet our Team
S. Parrish Winesett, MD, is a board-certified pediatric neurologist and pediatric epileptologist He has had extensive experience with complex epilepsy, including pre-surgical evaluations and advanced EED monitoring. He also has expertise in nonpharmagologic treatments for epilepsy, including vagal nerve stimulation and special diets, such as the ketogenic diet and the modified Atkins diet.
Dr. Winesett graduated from the University of Florida with a degree in microbiology and received his medical degree from the University of South Florida. He trained in pediatrics and internal medicine at the University of South Florida, child neurology at Vanderbilt University and epilepsy at the University of South Florida.
Hans H Shuhaiber, MD trained in Child Neurology, Medical Genetics, and Adult Neurology at Boston University, Columbia University- New York-Presbyterian, and NYU Langone Medical Center, provides the individualized treatment you need if you’ve been diagnosed with this complex and lifelong condition.
At UF Health, we offer comprehensive treatment and management options for all types of neurofibromatosis, a relatively rare genetic disorder that affects the development of nerve cells and sometimes causes tumors (neurofibromas) to develop in the nervous system.
Pediatric and Adult Specialty Service Providers
LAM is a rare cystic lung disease that almost always affects young females. It may occur for no reason (sporadic) or be associated with the disease Tuberous Sclerosis Complex (TSC). The University of Florida also has a dedicated lymphangioleiomyomatosis (LAM) clinic, accredited by the LAM Foundation, that focuses on the evaluation and management of patients with sporadic LAM and TSC-LAM. The clinic was established and run by Dr Ali Ataya of UF Pulmonary Medicine.