Our Labs

The UF Department of Neurology is home to a wide range of laboratories that support basic, translational, and clinical research across neurological diseases. These labs focus on areas such as neurodegenerative disorders, stroke and cerebrovascular disease, neuromuscular conditions, epilepsy, neuroimmunology, neurogenetics, and movement disorders, using approaches that range from molecular and cellular studies to advanced neuroimaging, electrophysiology, and patient-centered clinical research. Together, these diverse labs foster interdisciplinary collaboration and innovation, helping translate scientific discoveries into improved diagnosis, treatment, and care for patients with neurological conditions.

iBrain Lab

iBRAIN Lab integrates advanced neuroimaging and electrophysiology (MEG, intracranial EEG, fMRI) with AI-driven techniques, including deep learning, to investigate neurological disorders like epilepsy, Alzheimer’s Disease, Lewy Body dementia and Parkinson’s disease.

An individual undergoing MEG scan while engaging with visual stimuli displayed on a screen in front of her.

Laboratory of Neurogenetics and Neuroscience (LNN)

The laboratory’s research effort is dedicated to “predict and prevent” Parkinson’s disease through a combination of human genetic and omic analyses, molecular engineering and neuronal biology, mouse modeling, brain slice electrophysiology and pharmacology.

Test Tube

The LaVoie Lab

The LaVoie lab is primarily interested in the etiology of Parkinson’s disease, a neurologic disorder affecting more than 1 million Americans today. There are several inherited forms of Parkinson’s disease, and while these are very rare, we study the genetic forms of the disease in an effort to uncover the earliest molecular causes of the more common, sporadic forms of Parkinson’s disease.

Doctor Looking in Microscope

Neurotargets Fly Lab

The NeuroTargets Fly Lab focuses on the development and application of new technologies to define the molecular pathways leading to neurodegeneration and to identify potential therapeutic targets.

TDP fly brain

Neurocritical Care Lab

Our mission is to investigate the effects of self-fulfilling prophecy bias in neuroprognostication studies. We aim to improve neurocritical care through analysis of outcome prediction in cardiac arrest, stroke, intracerebral hemorrhage, traumatic brain injuries and subarachnoid hemorrhage. Our hope is to improve clinical outcomes for neurologic patients.

Abstract Brain Imagery

The Connect Lab

The Connect Lab investigates novel applications of technology in Lewy body dementia. We are developing a multi-disciplinary telemedicine program for individuals with Lewy body dementia and using wearable technology to collect vital information for clinical research. Our overarching goal is to connect those living with LBD and their loved ones to the specialty care they deserve.

brain waves

Megnetoencephalography – MEG

As one of approximately 200 MEG centers worldwide – and the only academic MEG center in Florida– our mission is to utilize this advanced technology to serve neurological patients and advance brain science. Our team of clinical experts uses MEG routinely for epilepsy and the planning of epilepsy surgery and brain tumor surgery in both adults and children. We are actively researching applications of MEG to understand movement disorders, dementias, and many other neurological conditions. In collaboration with basic scientists, we are using MEG to explore fundamental questions in the human neuroscience of movement, thought, memory, and consciousness.

patient on table getting a MEG

LBD Life Lab

The LBD Life Lab at UF explores the experiences of people living with Lewy body dementia from diagnosis to end of life. Our interdisciplinary team uses both qualitative (experience-based) and quantitative (data-based) approaches to understand the lived experiences of individuals with Lewy body dementia and their caregivers. The goal of our research group is to improve the lives of those affected by Lewy body dementia through purposeful conversation and innovation.

neurons