Prodip K Bose, MD, PhD
Associate Professor Of Anesthesiology, Neurology, & Physiological Sciences; Director, MRI & Translational Neurotrauma Rehabilitation Lab; Associate Director, Brain Rehabilitation Research Center
About Prodip K Bose
Prodip K. Bose, MD, PhD, joined us as an Associate Professor in 2020. He currently holds joint appointments as an Associate Professor in the Department of Neurology in the College of Medicine and McKnight Brain Institute and as an Associate Professor in the Department of Physiological Sciences in the College of Veterinary Medicine.
In addition, Dr. Bose is Director of the MRI and Translational Neurotrauma Rehabilitation Laboratory at the Malcom Randall VA Medical Center. He serves as Associate Director of the Brain Rehabilitation Research Center, a national center of the VA Rehabilitation Research & Development; Deputy Associate Chief of Staff/Research & Development for the Veterinary Medical Unit, North Florida/South Georgia Veterans Health System; and a member of the Editorial Board of the Neural Regeneration Research journal.
Dr. Bose, whose main areas of research are spinal cord injury, traumatic brain injury, and stroke, is also University of Florida Graduate Faculty in the College of Medicine Interdisciplinary Program and a member of several committees of the VA health system.
He earned his medical degree from the University of Dhaka in Bangladesh and did a fellowship in Neurology at Case Western Reserve University School of Medicine and Northeastern Ohio Universities College of Medicine. His PhD in Neuroscience was awarded by the University of Hong Kong.
Dr. Bose has contributed numerous peer-reviewed manuscripts, abstracts, and conference proceedings to his field and is currently involved as both a principal investigator and co-principal investigator on six active research grants.
Recently, attention has been given to develop a research program in the area of iron cheletor therapies aiming at to reduce neuro-inflammation and enhance neuroregeneration following neurotrauma (TBI and SCI), stroke, and Parkinson’s disease. The inflammatory burden initiated by injury/disease is further increased by iron derived from micro-bleeds which is known to act as a powerful promoter of chronic inflammation. Focus has been given to cellular and molecular neurobiology related to therapies-induced recovery of disabilities (spasticity/rigidity-motor, anxiety-like behavior, cognitive, balance and pain problems). Long-term focus of my laboratory research has been to understand the molecular-physiological-through-behavioral neurobiology of motor, sensory and cognitive plasticity following pharmacotherapy and neurorehabilitation using preclinical (rodent) models of neurotrauma (spinal cord, traumatic brain injuries, and stoke), and neurodegenerative/neuro-autoimmune diseases (e.g., PD, MS, ALS). Research focus has been directed to mechanism-based research studies that involve the development and testing of innovative translational targeted pharmacological therapies in conjunction to other complementary therapies (e.g., programmed locomotor exercise, transcranial magnetic stimulation, electrical stimulation on acupuncture points, stem cell and gene therapy) aimed at inducing guided plasticity and neuroregeneration, and ultimately reducing disabilities. A through drug toxicological studies using behavioral, physiological and histological measures are integral part of this therapeutic initiative.
Research program in the Bose Laboratory is supported by funding from US Department of Veterans Affair (list is not included here under funding), NIH, and several other funding agencies.