Michael Jaffee, M.D., FAAN, FANA
Chair And Professor Of Neurology
Department:
MD-NEUROLOGY-ADMIN/EDUC
Business Email:
michael.jaffee@ufl.edu
About Michael Jaffee
My name is Michael Jaffee, MD, FAAN, FANA, and I am a board-certified neurologist, the director of the University of Florida Brain Injury, Rehabilitation and Neuroresilience Center, and chair of the UF Department of Neurology.
I served 21 years in the United States Air Force (USAF), retiring at the rank of colonel in 2013. My USAF career included wartime service as the chief of medical staff for the largest U.S. military hospital in Iraq and as the USAF surgeon general neurology consultant. I was also the Department of Defense liaison to two White House-appointed panels of the Defense Health Board and the national director of the Defense and Veterans Brain Injury Center.
I graduated from the University of Virginia School of Medicine in 1992 and completed a combined residency in neurology and psychiatry at the San Antonio Uniformed Services Health Education Consortium in 1998. I went on to complete a sleep medicine fellowship there in 2011.
One of the first neurologists in the country to be certified in brain injury medicine, I see patients for a variety of neurological disorders, including traumatic brain injury, sports injuries, Alzheimer’s disease, dementias and sleep disorders.
Inspired by my father, an ENT physician who also trained in the Air Force and was dedicated to the public good, I became a neurologist with expertise in a broad range of neurological and psychological conditions so that I could help as many patients as possible.
Throughout my career, I have helped develop clinical practice guidelines and tools for the management of traumatic brain injury and have served as a consultant to the National Academy of Medicine, the North Atlantic Treaty Organization, the National Institutes of Health, and the National Football League.
My current research projects focus on better understanding risk factors and preclinical signs of dementia to include traumatic brain injuries and certain sleep disorders.
Teaching Profile
Courses Taught
2021-2024
PAS5020 Intro to Medicine 2
2021
MDC7800 Neurology Clerkship
Board Certifications
-
Behavioral Neurology and NeuropsychiatryUnited Council of Neurologic Subspecialties
-
Brain Injury MedicineAmerican Board of Psychiatry and Neurology
-
Neural Repair and RehabilitationUnited Council for Neurologic Subspecialties
-
NeurologyAmerican Board of Psychiatry and Neurology
-
PsychiatryAmerican Board of Psychiatry and Neurology
-
Sleep MedicineAmerican Board of Psychiatry and Neurology
Clinical Profile
Specialties
- Neurology
Areas of Interest
- Alzheimer Disease
- Concussion
- Dementia
- Sleep disorders
- Traumatic Brain Injury
Publications
Academic Articles
2024
Association of education attainment, smoking status, and alcohol use disorder with dementia risk in older adults: a longitudinal observational study.
Alzheimer's research & therapy.
16(1)
[DOI] 10.1186/s13195-024-01569-7.
[PMID] 39294787.
2024
Continuous glucose monitoring and all-cause mortality in insulin-using population with diabetes and cognitive impairment.
Diabetes, obesity & metabolism.
26(10):4795-4798
[DOI] 10.1111/dom.15842.
[PMID] 39134460.
2024
Functional and free-water imaging in rapid eye movement behaviour disorder and Parkinson’s disease.
Brain communications.
6(5)
[DOI] 10.1093/braincomms/fcae344.
[PMID] 39411244.
2024
Heterogeneous treatment effects of sodium-glucose cotransporter 2 inhibitors on risk of dementia in people with type 2 diabetes: A population-based cohort study.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
20(8):5528-5539
[DOI] 10.1002/alz.14048.
[PMID] 38958394.
2024
Preliminary evidence of transcutaneous vagus nerve stimulation effects on sleep in veterans with post-traumatic stress disorder.
Journal of sleep research.
33(1)
[DOI] 10.1111/jsr.13891.
[PMID] 37039398.
2024
Promoting Growth in Behavioral Neurology: A Path Forward.
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.
37(2):49-56
[DOI] 10.1097/WNN.0000000000000368.
[PMID] 38717325.
2023
A Computable Phenotype for the Identification of Sexual and Gender Minorities in Electronic Health Records.
AMIA … Annual Symposium proceedings. AMIA Symposium.
2023:1057-1066
[PMID] 38222414.
2023
Distinct cortical and subcortical predictors of Purdue Pegboard decline in Parkinson’s disease and atypical parkinsonism.
NPJ Parkinson's disease.
9(1)
[DOI] 10.1038/s41531-023-00521-0.
[PMID] 37277372.
2023
Effects of sleep disturbance on trauma-focused psychotherapy outcomes in posttraumatic stress disorder: A systematic review.
Annals of the New York Academy of Sciences.
1526(1):30-49
[DOI] 10.1111/nyas.15029.
[PMID] 37393069.
2022
A consensus on optimization of care in patients with growth hormone deficiency and mild traumatic brain injury.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
66
[DOI] 10.1016/j.ghir.2022.101495.
[PMID] 35933894.
2022
Impacts of Eligibility Criteria on Trial Participants’ Age in Alzheimer’s Disease Clinical Trials.
AMIA … Annual Symposium proceedings. AMIA Symposium.
2022:368-376
[PMID] 37128470.
2022
Neurology Access Clinic: A Model to Improve Access to Neurologic Care in an Academic Medical Center.
Neurology. Clinical practice.
12(3):203-210
[DOI] 10.1212/CPJ.0000000000001158.
[PMID] 35747536.
2022
Prevalence of Alzheimer’s and Related Dementia Diseases and Risk Factors Among Transgender Adults, Florida, 2012‒2020.
American journal of public health.
112(5):754-757
[DOI] 10.2105/AJPH.2022.306720.
[PMID] 35324265.
2021
Behavioral and Cognitive Aspects of Concussion.
Continuum (Minneapolis, Minn.).
27(6):1646-1669
[DOI] 10.1212/CON.0000000000001057.
[PMID] 34881730.
2021
Impact of a Sleep Enhancement Protocol on Nighttime Room Entries in an Inpatient Rehabilitation Facility.
Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses.
46(4):232-243
[DOI] 10.1097/RNJ.0000000000000291.
[PMID] 32976220.
2021
Making a Difference: Affective Distress Explains Discrepancy Between Objective and Subjective Cognitive Functioning After Mild Traumatic Brain Injury.
The Journal of head trauma rehabilitation.
36(3):186-195
[DOI] 10.1097/HTR.0000000000000618.
[PMID] 32898033.
2021
Posttraumatic Stress Disorder and Anxiety-Related Conditions.
Continuum (Minneapolis, Minn.).
27(6):1738-1763
[DOI] 10.1212/CON.0000000000001054.
[PMID] 34881734.
2021
Quality Improvement in Neurology: Concussion Quality Measurement Set.
Neurology.
97(11):537-542
[DOI] 10.1212/WNL.0000000000012537.
[PMID] 34321361.
2020
Acute Effects of Sport-Related Concussion on Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase L1, Total Tau, and Neurofilament Light Measured by a Multiplex Assay.
Journal of neurotrauma.
37(13):1537-1545
[DOI] 10.1089/neu.2019.6831.
[PMID] 32024456.
2020
Estimating minimal clinically important differences for two scales in patients with chronic traumatic brain injury.
Current medical research and opinion.
36(12):1999-2007
[DOI] 10.1080/03007995.2020.1841616.
[PMID] 33095678.
2020
King-Devick Test Time Varies by Testing Modality.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.
30(5):e139-e142
[DOI] 10.1097/JSM.0000000000000691.
[PMID] 30358616.
2020
Should Neurologists Be Concerned With REM Sleep Quantity?
JAMA neurology.
77(10):1209-1210
[DOI] 10.1001/jamaneurol.2020.2122.
[PMID] 32663238.
2019
Drill-Specific Head Impacts in Collegiate Football Practice: Implications for Reducing “Friendly Fire” Exposure.
Annals of biomedical engineering.
47(10):2094-2108
[DOI] 10.1007/s10439-018-2088-5.
[PMID] 29987539.
2019
Exploratory study of sport-related concussion effects on peripheral micro-RNA expression.
Brain injury.
33(4):1-7
[DOI] 10.1080/02699052.2019.1573379.
[PMID] 30704304.
2019
Patient-perceived value of a specialty-specific welcome letter: What you say and how you say it.
Neurology. Clinical practice.
9(3):228-232
[DOI] 10.1212/CPJ.0000000000000633.
[PMID] 31341710.
2019
Predicting long-term cognitive and neuropathological consequences of moderate to severe traumatic brain injury: Review and theoretical framework.
Journal of clinical and experimental neuropsychology.
41(8):775-785
[DOI] 10.1080/13803395.2019.1620695.
[PMID] 31156042.
2018
Concussion BASICS II: Baseline serum biomarkers, head impact exposure, and clinical measures.
Neurology.
91(23):e2123-e2132
[DOI] 10.1212/WNL.0000000000006616.
[PMID] 30404782.
2018
Concussion Biomarkers Assessed in Collegiate Student-Athletes (BASICS) I: Normative study.
Neurology.
91(23):e2109-e2122
[DOI] 10.1212/WNL.0000000000006613.
[PMID] 30404785.
2018
Diffusion tensor imaging (DTI) findings in adult civilian, military, and sport-related mild traumatic brain injury (mTBI): a systematic critical review.
Brain imaging and behavior.
12(2):585-612
[DOI] 10.1007/s11682-017-9708-9.
[PMID] 28337734.
2018
Glymphatic system disruption as a mediator of brain trauma and chronic traumatic encephalopathy.
Neuroscience and biobehavioral reviews.
84:316-324
[DOI] 10.1016/j.neubiorev.2017.08.016.
[PMID] 28859995.
2018
Long-term Mortality in NFL Professional Football Players: No Significant Increase, but Questions Remain.
JAMA.
319(8):773-775
[DOI] 10.1001/jama.2017.20885.
[PMID] 29392297.
2018
Military-related risk factors for dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
14(12):1651-1662
[DOI] 10.1016/j.jalz.2018.08.011.
[PMID] 30415806.
2018
Tau in Chronic Traumatic Encephalopathy-Reply.
JAMA neurology.
75(3):381-382
[DOI] 10.1001/jamaneurol.2017.4893.
[PMID] 29404562.
2017
Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review.
JAMA neurology.
74(10):1255-1262
[DOI] 10.1001/jamaneurol.2017.2396.
[PMID] 28975240.
2016
Factors Influencing Clinical Correlates of Chronic Traumatic Encephalopathy (CTE): a Review.
Neuropsychology review.
26(4):340-363
[PMID] 27561662.
2016
Parkinson’s disease psychosis: therapy tips and the importance of communication between neurologists and psychiatrists.
Neurodegenerative disease management.
6(4):319-30
[DOI] 10.2217/nmt-2016-0009.
[PMID] 27408981.
2016
The Danger of Not Treating Parkinson Disease Psychosis.
JAMA neurology.
73(9)
[DOI] 10.1001/jamaneurol.2016.2280.
[PMID] 27400122.
2015
Sleep disturbances in athletic concussion.
Brain injury.
29(2):221-7
[DOI] 10.3109/02699052.2014.983978.
[PMID] 25587746.
2014
Day of injury cognitive performance on the Military Acute Concussion Evaluation (MACE) by U.S. military service members in OEF/OIF.
Military medicine.
179(9):990-7
[DOI] 10.7205/MILMED-D-13-00349.
[PMID] 25181717.
2013
Military risk factors for Alzheimer’s disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
9(4):445-51
[DOI] 10.1016/j.jalz.2013.03.005.
[PMID] 23809365.
2010
Combat-related traumatic brain injury and its implications to military healthcare.
The Psychiatric clinics of North America.
33(4):783-96
[DOI] 10.1016/j.psc.2010.08.007.
[PMID] 21093678.
2010
Defense and Veterans Brain Injury Center: program overview and research initiatives.
Military medicine.
175(7 Suppl):37-41
[PMID] 23634477.
2010
Military traumatic brain injury and blast.
NeuroRehabilitation.
26(3):179-81
[DOI] 10.3233/NRE-2010-0553.
[PMID] 20448307.
2010
The history and evolution of traumatic brain injury rehabilitation in military service members and veterans.
American journal of physical medicine & rehabilitation.
89(8):688-94
[DOI] 10.1097/PHM.0b013e3181e722ad.
[PMID] 20647782.
2010
Traumatic brain injury, posttraumatic stress disorder, and postconcussive symptom reporting among troops returning from iraq.
The Journal of head trauma rehabilitation.
25(5):307-12
[DOI] 10.1097/HTR.0b013e3181cada03.
[PMID] 20042982.
2009
A brief overview of traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) within the Department of Defense.
The Clinical neuropsychologist.
23(8):1291-8
[DOI] 10.1080/13854040903307250.
[PMID] 19882472.
2009
Acute clinical care and care coordination for traumatic brain injury within Department of Defense.
Journal of rehabilitation research and development.
46(6):655-66
[PMID] 20104395.
2009
Case report of a soldier with primary blast brain injury.
NeuroImage.
47 Suppl 2:T152-3
[DOI] 10.1016/j.neuroimage.2009.01.060.
[PMID] 19457364.
2009
Computational biology – modeling of primary blast effects on the central nervous system.
NeuroImage.
47 Suppl 2:T10-20
[DOI] 10.1016/j.neuroimage.2009.02.019.
[PMID] 19248833.
2009
Head injury as a PTSD predictor among Oklahoma City bombing survivors.
The Journal of trauma.
67(6):1311-9
[DOI] 10.1097/TA.0b013e31819adc36.
[PMID] 20009683.
2009
Traumatic brain injury research opportunities: results of Department of Veterans Affairs Consensus Conference.
Journal of rehabilitation research and development.
46(6):vii-xvi
[PMID] 20104393.
2007
Posttraumatic stress disorder and posttraumatic stress disorder-like symptoms and mild traumatic brain injury.
Journal of rehabilitation research and development.
44(7):895-920
[PMID] 18075948.
2007
Team approach to diagnosis and management of traumatic brain injury and its comorbidities.
Journal of rehabilitation research and development.
44(7):vii-xi
[PMID] 18075945.
2005
The neurology of aviation, underwater, and space environments.
Neurologic clinics.
23(2):541-52
[PMID] 15757796.
Grants
Jan 2024
– Jan 2025
ACTS (AD Clinical Trial Simulation): Developing Advanced Informatics Approaches for an Alzheimer's Disease Clinical Trial Simulation System
Role: Co-Investigator
Funding: MAYO CLINIC
via NATL INST OF HLTH NIA
Sep 2023
ACTIVE
Building a system of resource facilitation for all Floridians with brain injury
Role: Principal Investigator
Funding: ADMIN FOR COMMUNITY LIVING
Sep 2023
– Jan 2025
Post-Acute Sequelae of SARS-CoV-2 Infection and Subsequent Disease Progression in Individuals with Alzheimer's Disease (AD) and Its Related Dementias (ADRD): Influence of the Social and Environmental Determinants of Health
Role: Co-Investigator
Funding: BRIGHAM AND WOMENS HOSPITAL
via NATL INST OF HLTH NIA
Sep 2023
– Jan 2024
ACTS (AD Clinical Trial Simulation): Developing Advanced Informatics Approaches for an Alzheimer's Disease Clinical Trial Simulation System
Role: Co-Investigator
Funding: UNIV OF TEXAS HLTH SCI CTR AT HOUSTON
via NATL INST OF HLTH NIA
Aug 2023
ACTIVE
Research Coordinator CTOA
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Jul 2023
ACTIVE
Memory Disorder Clinic 7/1/2023 – 6/30/2026
Role: Principal Investigator
Funding: FL DEPT OF ELDER AFFAIRS
Jun 2023
– Mar 2025
Consulting – Virtual Integrated Social Task (VISTa)
Role: Principal Investigator
Funding: FL INST FOR HUMAN AND MACHINE COGNITION
via US ARMY MED RES ACQUISITION
May 2023
ACTIVE
AI-ADRD: Accelerating interventions of AD/ADRD via Machine learning methods
Role: Co-Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH NIA
Feb 2023
ACTIVE
Disparities of Alzheimer's disease progression in sexual and gender minorities
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Jul 2022
– Jun 2023
Memory Disorder Clinic Year 5
Role: Principal Investigator
Funding: FL DEPT OF ELDER AFFAIRS
Jan 2022
ACTIVE
Alzheimer's Disease Staging from EEG and Neurovascular Clinical Data
Role: Co-Project Director/Principal Investigator
Funding: APPLIED COGNITION
Aug 2021
ACTIVE
Preclinical Markers of Parkinsonism
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Aug 2020
– Apr 2024
Optimizing the Population Representativeness of Older Adults in Alzheimer's Disease and Related Dementia Clinical Trials
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Aug 2020
– Jan 2024
Using Electronic Health Records from a Large Clinical Data Research Network to Understand Cancer Burden and Cancer Risks Among Transgender and Gender Nonconforming (TGNC) Individuals
Role: Project Manager
Funding: NATL INST OF HLTH NCI
Jun 2020
– May 2024
Transcutaneous Vagal Nerve Stimulation Improvement of Sleep Quality in Veterans with PTSD with or without History of TBI
Role: Principal Investigator
Funding: US DEPT OF VETERANS AFFAIRS
Feb 2020
– Feb 2025
CTOA – Supplies
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Jan 2020
– Dec 2024
The benefits and harms of lung cancer screening in Florida
Role: Project Manager
Funding: NATL INST OF HLTH NCI
Jan 2020
– Jun 2021
Mangurian RAPID EYE MOVEMENT BEHAVIOR DISORDER AS A PRECLINICAL MODEL OF DEMENTIA AND PARKINSONISM
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2019
– Jun 2022
Memory Disorder Clinic
Role: Principal Investigator
Funding: FL DEPT OF ELDER AFFAIRS
Jan 2019
– Nov 2022
Systematic Analysis of Clinical Study Generalizability Assessment Methods with Informatics
Role: Co-Investigator
Funding: FL STATE UNIV
via NATL INST OF HLTH NIA
Jul 2017
– Jun 2019
MEMORY DISORDER CLINIC
Role: Principal Investigator
Funding: FL DEPT OF ELDER AFFAIRS
Jul 2016
– Jun 2017
ALZHEIMERS DISEASE INITIATIVE MEMORY DISORDER CLINIC 2016-2017
Role: Principal Investigator
Funding: FL DEPT OF ELDER AFFAIRS
Jan 2014
– Dec 2023
CTOA – Administrative
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Jul 2006
– Sep 2024
BRAIN AND SPINAL CORD INJURY RESEARCH
Role: Project Manager
Funding: FL DEPT OF HLTH
Education
Fellowship – Sleep Medicine
2010-2011
·
San Antonio Uniformed Services Health Education Consortium
Residency – Neurology
1998
·
San Antonio Uniformed Services Health Education Consortium
Residency – Psychiatry
1998
·
San Antonio Uniformed Services Health Education Consortium
Medical Degree
1992
·
University of Virginia
Contact Details
Emails:
- Business:
- michael.jaffee@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100268
GAINESVILLE FL 32610 - Business Street:
-
3011 SW WILLISTON RD RM 1103
GAINESVILLE FL 32608