Yuqing Li

Yuqing Li, PhD

Professor Of Neurology

Department: MD-NEUROLOGY-MOVEMENT DISORDER
Business Phone: (352) 273-6546
Business Email: yuqingli@ufl.edu

About Yuqing Li

Dr. Li’s research is mainly focused on the pathophysiology and experimental therapeutics of dystonia and restless legs syndrome. He is also broadly interested in animal models of movement disorders, basal ganglia and cerebellum, and molecular and cellular mechanisms of synaptic plasticity during development and learning. His lab’s expertise is to perform conditional mutagenesis and AAV infection in mice where selected genes are altered in specific neurons or circuits in the brain during a defined period throughout the animal’s life cycle. His lab also uses C. elegans to dissect gene-gene interaction and gene function. This powerful approach allows Dr. Li and his co-workers to apply functional genomics, in vitro electrophysiology, in vivo animal imaging, neurochemistry, optogenetic or chemogenetic approaches to understand the pathogenesis of neurological disorders and to develop an effective treatment.

Research Profile

Dr. Li’s research is mainly focused on pathophysiology and experimental therapeutics of dystonia and restless legs syndrome. He is also broadly interested in animal models of movement disorders and in molecular and cellular mechanisms of synaptic plasticity during development and learning. His lab’s expertise is to perform conditional mutagenesis in mouse where selected genes are altered in specific neurons or circuits in the brain and in defined period during animal’s development. This powerful approach allows Dr. Li and his co-workers to apply functional genomics and other multidisciplinary approaches to understand the pathogenesis of neurological disorders and to develop effective treatment.

Publications

2017 Sleep Medicine
2013 Movement Disorders

Grants

Sep 2018 ACTIVE
Non-Invasive Markers of Neurodegeneration in Movement Disorders
NATL INST OF HLTH NINDS · Project Manager
Jan 2016 – Dec 2018
Opioid System and Restless Syndrome: A Knockout Mouse Approach to Elucidate Its Role
MUNDIPHARMA RESEARCH LTD · Principal Investigator
Aug 2015 – Jul 2016
characterization of meisl heterozygous knockout mice
RESTLESS LEGS SYNDROME FOUNDATION · Principal Investigator
Jan 2014 – Mar 2020
Restless Legs Syndrome: Pathophysiology using Btbd9 Conditional Knockout Mice
NATL INST OF HLTH NINDS · Principal Investigator
Jul 2011 – Dec 2016
Pathophysiology of DYT1 Dystonia: Targeted Mouse Models
UF FOU · Principal Investigator
May 2011 – Dec 2016
RLS replacement for 94393
UF FOU · Principal Investigator
May 2011 – Dec 2016
P50 companion project to 00105729
UF FOU · Principal Investigator
May 2011 – Dec 2016
DYT12 Companion to 00094395
UF FOU · Principal Investigator
May 2011 – Dec 2016
epsilon-sarcoglycan UFF to 94399 R03
UF FOU · Principal Investigator

Contact Details

Phones:
Business:
(352) 273-6546
Emails:
Business:
yuqingli@ufl.edu