Sub Subramony

Sub Subramony, M.D.

Professor

Department: MD-NEUROMUSCULAR NEUROLOGY
Business Phone: (352) 273-5000

About Sub Subramony

Dr. S. H. Subramony was trained in Neurology and Electromyography/ Neuromuscular diseases at the Cleveland Clinic, Cleveland, OH. Subsequent to that, he was on the faculty at the University of Mississippi Medical Center from (from 1980 to 2007), where he was named the Billy Guyton Distinguished Professor of Neurology. Later, at University of Texas Medical Branch in Galveston where he was appointed the Charlotte Warmoth Professor of Neurology (2007 to 2009 ), before coming to University of Florida in 2009. He has directed the adult Muscular Dystrophy clinics and the Ataxia Clinic at UF since then.

Over the last 25 years, he has had an investigative interest in genetically determined neuromuscular disorders and hereditary ataxias. He was an active participant in many gene identification studies in these disorders and more recently has been focused on translational research to bring innovative therapies to these disorders. He has active collaborations with the Powell Gene Therapy center and the Center for Neurogenetics at UF allowing for bench to bedside translation. He is an active member of national study groups in Friedreich Ataxia, myotonic muscular dystrophy and spinocerebellar ataxias and site investigator for federally funded clinical research studies in all these disorders. In addition, he is the site investigator for many industry funded clinical trials in these diseases. Dr. Subramony is considered one of the world leading experts in these fields.

His clinical experience includes the management of patients with all types of neuromuscular diseases including ALS, myasthenia gravis, polymyositis, neuropathies and muscular dystrophies. Currently he focuses on genetic neuromuscular diseases and ataxias and offers treatment that includes electromyography, muscle biopsy when appropriate, appropriate genetic testing and referral to ancillary services such as physical, occupational and speech therapy and evaluation for mobility aids.

Accomplishments

Ron Bartek award for promoting research in Friedirech Ataxia
2018 · Friedreich Ataxia Research Alliance
Billy Guyton Distinguished Professor
2004-2009 · University of Mississippi
Neuroscience Alumnus of the year
1992 · The Cleveland Clinic Foundation

Board Certifications

  • American Board of Neurology, special certificate in Neuromuscular Medicine
    American Baord of Psychiatry and Neurology
  • Neurology
    American Board of Psychiatry and Neurology

Clinical Profile

Specialties
  • Neurology
Subspecialties
  • Neuromuscular Medicine
Areas of Interest
  • Amyotrophic lateral sclerosis (ALS)
  • Becker muscular dystrophy
  • Duchenne muscular dystrophy
  • Friedreich ataxia
  • Movement – uncoordinated
  • Muscular dystrophy
  • Myasthenia gravis
  • Myotonia congenita
  • Neuromuscular disorders
  • Peripheral neuropathy

Research Profile

My key research interests include phenotypic characterization, phenotype-genotype correlations and pathogenic mechansims in genetically induced cerebellar ataxias and muscular dystrophies. In addition, I also am interested in developing assessment methods, biomarker discovery and therapeutic modalities for such diseases.

Publications

2020 Journal of the Neurological Sciences
2013 Developmental Medicine and Child Neurology
2012 Journal of the Neurological Sciences
2011 Zhongnan Daxue xuebao.

Grants

May 2020 – Jun 2020
HB9053 2019 – Center of Excellence for Friedreich's Ataxia Research
FL DEPT OF HLTH · Principal Investigator
Jul 2019 ACTIVE
Myotonic Dystrophy Clinical Research Network
UNIV OF ROCHESTER · Principal Investigator
Apr 2019 ACTIVE
Butler Research Neurology-Social Cognition: Brain imaging and social cognition in myotonic dystrophy (DM) type 1
UF FOU · Principal Investigator
Apr 2019 ACTIVE
Martino Research Fund-Social Cognition-ENDM1 Travel
UF FOU · Principal Investigator
Jan 2019 ACTIVE
Clinical Trial Readiness for SCA1 and SCA3 – Year 2
METHODIST HOSPITAL RESEARCH INSTITUTE · Principal Investigator
Jan 2019 – Dec 2019
Clinical Trial Readiness for SCA1 and SCA3
METHODIST HOSPITAL RESEARCH INSTITUTE · Principal Investigator
Nov 2018 ACTIVE
Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type-1 (END-DM1) "Study"
VA COMMONWEALTH UNIV · Principal Investigator
Jun 2018 ACTIVE
FARA-Supplemental Funding for AWD02770 FDA CHOP-Natural History of Friedreich Ataxia in Children
FRIEDRICH'S ATAXIA RESEARCH ALLIANCE · Principal Investigator
Jun 2018 – May 2019
Collaborative Clinical Research Network in FA
FRIEDRICH'S ATAXIA RESEARCH ALLIANCE · Principal Investigator
Jan 2018 – Dec 2018
Clinical Trial Readiness for SCA1 and SCA3
METHODIST HOSPITAL RESEARCH INSTITUTE · Principal Investigator
Sep 2017 ACTIVE
Natural history of Friedreich ataxia in children
CHILDRENS HOSP PHILADELPHIA · Principal Investigator
Jul 2017 – Jul 2020
Personalized dosing of dichloroacetate for the treatment of rare and common diseases
MEDOSOME BIOTEC ·
Jul 2017 – Jun 2018
2017 MDF Conference Travel Grant
MYOTONIC DYSTROPHY FOU · Principal Investigator
Jun 2017 – May 2018
Collaborative Clinical Research Network in Friedreich Ataxia
FRIEDRICH'S ATAXIA RESEARCH ALLIANCE · Principal Investigator
Jan 2017 ACTIVE
Muscular Dystrophy Association Clinic Grants
MUSCULAR DYSTROPHY ASSO · Principal Investigator
Jun 2016 – Aug 2018
Development of Magnetic Resonance Imaging as an Endpoint in Myotonic Dystrophy Type 1
WYCK FOUNDATION ·
Jun 2016 – May 2017
Collaborative Clinical Research Network in Friedreich Ataxia (CCRN in FA)
FRIEDRICH'S ATAXIA RESEARCH ALLIANCE · Principal Investigator
Jan 2016 – Dec 2018
Myotonic Dystrophy Clinical Research Network
UNIV OF ROCHESTER · Principal Investigator
Dec 2015 – May 2017
Multicenter, Safety and Efficacy, Open-Label Extension Study of ACTIMMUNE? (interferon ?-1b) in Children and Young Adults with Friedreichs Ataxia
UNIV OF ROCHESTER · Principal Investigator
Sep 2015 – Aug 2018
Dysmetria and Motor Function in SCA: Mechanisms and Rehabilitation
NATL INST OF HLTH NINDS · Project Manager
Sep 2015 – May 2020
Partnership For Magnetic Resonance Spectroscopy Biomarker Development
UNIV OF MINNESOTA · Project Manager
Jul 2015 – Jun 2018
Pathophysiology of Upper and Lower Limb Motor Control
NATL INST OF HLTH NINDS · Project Manager
Jun 2015 – May 2016
Collaborative Clinical Research Network in Friedreich's
FRIEDRICH'S ATAXIA RESEARCH ALLIANCE · Principal Investigator
Mar 2015 – May 2017
A Randomized, Multicenter, Double-blind, Placebo Control
UNIV OF ROCHESTER · Principal Investigator
Dec 2014 ACTIVE
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Friedreichs Ataxia
TRIAL RUNNERS LLC · Principal Investigator
Nov 2014 – Nov 2017
A Phase 1/2a Blinded, Placebo-Controlled Study to Assess the Safety, Tolerability, and Dose-range Finding of Multiple Ascending Doses of ISIS 598769 Administered Subcutaneously to Adult Patients with Myotonic Dystrophy Type 1
INC RESEARCH INC · Principal Investigator
Jan 2014 – Mar 2016
DM1
MYOTONIC DYSTROPHY FOU · Principal Investigator
Jul 2007 – Aug 2016
Clinical and Translational Science Institute
UF RESEARCH FOU · Project Manager
Jan 2001 – Dec 2016
00112204
MUSCULAR DYSTROPHY ASSO · Principal Investigator

Education

Fellowship – Clinical Neurophysiology
1979 · Cleveland Clinic
Fellowship – Neurology
1978 · Cleveland Clinic
Internship
1975 · MacNeal Hospital
Bachelor of Medicine, Bachelor of Surgery
1971 · University of Delhi, Maulana Azad Medical College

Contact Details

Phones:
Business:
(352) 273-5000
Emails: