Leonardo Brito de Almeida

Leonardo Brito de Almeida, MD, MS

Assistant Professor

Department: MD-NEUROLOGY-MOVEMENT DISORDER
Business Phone: (352) 294-5000
Business Email: l.almeida@ufl.edu

About Leonardo Brito de Almeida

Leonardo Brito de Almeida, MD, MS is a neurologist and an assistant professor with the department of neurology at the University of Florida College of Medicine.

Dr. Almeida earned both his master’s degree in medicine and health and his medical degree from the Universidade Federal da Bahia in Brazil. After graduation, he pursued his neurology residency at the University of Alabama at Birmingham where he was the chief resident of neurology. He then completed his movement disorders fellowship at UF.

Dr. Almeida is board-certified in neurology by the American Board of Psychiatry and Neurology. He has contributed to over 50 publications, with much of his work focusing on deep brain stimulation, Parkinson’s disease and movement disorders. He currently serves on UF Health’s Norman Fixel Institute of Neurological Diseases INFORM Database Access Committee and is a part of multiple study groups. Dr. Almeida is also fluent in English and Portuguese.

Teaching Profile

Courses Taught
2021
MDC7800 Neurology Clerkship

Board Certifications

  • Neurology
    The American Board of Psychiatry and Neurology

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Deep brain stimulation
  • Dystonia
  • Tremor disorders

Research Profile

Areas of Interest
  • Deep brain stimulation
  • Parkinson’s disease
  • tremor
Open Researcher and Contributor ID (ORCID)

0000-0002-0921-887X

Publications

2022
Directional Deep Brain Stimulation for Parkinson’s Disease: Results of an International Crossover Study With Randomized, Double-Blind Primary Endpoint
Neuromodulation: Technology at the Neural Interface. 25(6):817-828 [DOI] 10.1111/ner.13407.
2021
Brain structures and networks responsible for stimulation-induced memory flashbacks during forniceal deep brain stimulation for Alzheimer’s disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 17(5):777-787 [DOI] 10.1002/alz.12238. [PMID] 33480187.
2021
Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation.
Brain : a journal of neurology. 144(6):1774-1786 [DOI] 10.1093/brain/awab074. [PMID] 33889943.
2021
Corrigendum to: Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation.
Brain : a journal of neurology. 144(8) [DOI] 10.1093/brain/awab192. [PMID] 34115824.
2021
Deep brain stimulation programming strategies: segmented leads, independent current sources, and future technology
Expert Review of Medical Devices. 18(9):875-891 [DOI] 10.1080/17434440.2021.1962286.
2021
Geospatial Analysis of Persons with Movement Disorders Living in Underserved Regions
Tremor and Other Hyperkinetic Movements. 11(1) [DOI] 10.5334/tohm.635. [PMID] 34513276.
2021
Globus Pallidus Internus (GPi) Deep Brain Stimulation for Parkinson’s Disease: Expert Review and Commentary.
Neurology and therapy. 10(1):7-30 [DOI] 10.1007/s40120-020-00220-5. [PMID] 33140286.
2021
Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation.
Brain : a journal of neurology. 144(9):2837-2851 [DOI] 10.1093/brain/awab170. [PMID] 33905474.
2021
Pallidal Connectivity Profiling of Stimulation-Induced Dyskinesia in Parkinson’s Disease.
Movement disorders : official journal of the Movement Disorder Society. 36(2):380-388 [DOI] 10.1002/mds.28324. [PMID] 33002233.
2021
Safety and Tolerability of Burst-Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease.
Frontiers in human neuroscience. 15 [DOI] 10.3389/fnhum.2021.651168. [PMID] 33981207.
2020
An International Survey of Deep Brain Stimulation Utilization in Asia and Oceania: The DBS Think Tank East.
Frontiers in human neuroscience. 14 [DOI] 10.3389/fnhum.2020.00162. [PMID] 32733215.
2020
Brain Atrophy Following Deep Brain Stimulation: Management of a Moving Target.
Tremor and other hyperkinetic movements (New York, N.Y.). 10 [DOI] 10.5334/tohm.546. [PMID] 33133768.
2020
Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction.
Frontiers in human neuroscience. 14 [DOI] 10.3389/fnhum.2020.583441. [PMID] 33240065.
2020
Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
Science Translational Medicine. 12(572) [DOI] 10.1126/scitranslmed.aay7680. [PMID] 33268512.
2020
Combined Unilateral Subthalamic Nucleus and Contralateral Globus Pallidus Interna Deep Brain Stimulation for Treatment of Parkinson Disease: A Pilot Study of Symptom-Tailored Stimulation.
Neurosurgery. 87(6):1139-1147 [DOI] 10.1093/neuros/nyaa201. [PMID] 32459849.
2020
Functional and Structural Connectivity Patterns Associated with Clinical Outcomes in Deep Brain Stimulation of the Globus Pallidus Internus for Generalized Dystonia
American Journal of Neuroradiology. 41(3):508-514 [DOI] 10.3174/ajnr.a6429.
2020
Long-term Parkinson’s disease quality of life after staged DBS: STN vs GPi and first vs second lead
npj Parkinson's Disease. 6(1) [DOI] 10.1038/s41531-020-0115-3. [PMID] 32656315.
2020
Neuroimaging Advances in Deep Brain Stimulation: Review of Indications, Anatomy, and Brain Connectomics
American Journal of Neuroradiology. 41(9):1558-1568 [DOI] 10.3174/ajnr.a6693.
2020
Parkinson’s disease motor subtype changes during 20 years of follow-up.
Parkinsonism & related disorders. 76:104-107 [DOI] 10.1016/j.parkreldis.2019.05.024. [PMID] 31129020.
2020
Parkinson’s disease motor subtypes and bilateral GPi deep brain stimulation: One-year outcomes.
Parkinsonism & related disorders. 75:7-13 [DOI] 10.1016/j.parkreldis.2020.05.004. [PMID] 32428801.
2019
An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
Tremor and other hyperkinetic movements (New York, N.Y.). 9 [DOI] 10.7916/d8-xj6w-cm53. [PMID] 30867977.
2019
Fornix-Region Deep Brain Stimulation-Induced Memory Flashbacks in Alzheimer’s Disease.
The New England journal of medicine. 381(8):783-785 [DOI] 10.1056/NEJMc1905240. [PMID] 31433930.
2019
New Onset On-Medication Freezing of Gait After STN-DBS in Parkinson’s Disease.
Frontiers in neurology. 10 [DOI] 10.3389/fneur.2019.00659. [PMID] 31275238.
2019
Rescue levodopa-carbidopa intestinal gel (LCIG) therapy in Parkinson’s disease patients with suboptimal response to deep brain stimulation.
Annals of clinical and translational neurology. 6(10):1989-1995 [DOI] 10.1002/acn3.50889. [PMID] 31518070.
2018
Deep Brain Stimulation for Parkinson Disease Dementia: A New Frontier?
JAMA neurology. 75(2):152-153 [DOI] 10.1001/jamaneurol.2017.3798. [PMID] 29255840.
2018
Segmentation of the Globus Pallidus Internus Using Probabilistic Diffusion Tractography for Deep Brain Stimulation Targeting in Parkinson Disease
American Journal of Neuroradiology. 39(6):1127-1134 [DOI] 10.3174/ajnr.a5641.
2018
Square biphasic pulse deep brain stimulation for essential tremor: The BiP tremor study
Parkinsonism & Related Disorders. 46:41-46 [DOI] 10.1016/j.parkreldis.2017.10.015.
2018
Structural connectivity-based segmentation of the thalamus and prediction of tremor improvement following thalamic deep brain stimulation of the ventral intermediate nucleus.
NeuroImage. Clinical. 20:1266-1273 [DOI] 10.1016/j.nicl.2018.10.009. [PMID] 30318403.
2017
A pilot trial of square biphasic pulse deep brain stimulation for dystonia: The BIP dystonia study
Movement Disorders. 32(4):615-618 [DOI] 10.1002/mds.26906.
2017
Biomechanical Analysis of Dance for Parkinson’s Disease: a Paradoxical Case Study of Balance and Gmt Effects?
EXPLORE. 13(6):409-413 [DOI] 10.1016/j.explore.2017.03.009.
2017
Depressive Symptoms are Frequent in Atypical Parkinsonian Disorders
Movement Disorders Clinical Practice. 4(2):191-197 [DOI] 10.1002/mdc3.12382. [PMID] 28944256.
2017
Variable frequency stimulation of subthalamic nucleus in Parkinson’s disease: Rationale and hypothesis.
Parkinsonism & related disorders. 39:27-30 [DOI] 10.1016/j.parkreldis.2017.03.015. [PMID] 28392298.
2016
Association between antidepressants and falls in Parkinson’s disease.
Journal of neurology. 263(1):76-82 [DOI] 10.1007/s00415-015-7947-5. [PMID] 26514836.
2016
Deep Brain Stimulation Battery Longevity: Comparison of Monopolar Versus Bipolar Stimulation Modes
Movement Disorders Clinical Practice. 3(4):359-366 [DOI] 10.1002/mdc3.12285. [PMID] 27617270.
2016
Occurrence of Dysphagia Following Botulinum Toxin Injection in Parkinsonism-related Cervical Dystonia: A Retrospective Study.
Tremor and other hyperkinetic movements (New York, N.Y.). 6 [PMID] 27830106.
2015
Chasing tics in the human brain: development of open, scheduled and closed loop responsive approaches to deep brain stimulation for tourette syndrome.
Journal of clinical neurology (Seoul, Korea). 11(2):122-31 [DOI] 10.3988/jcn.2015.11.2.122. [PMID] 25851890.
2015
Rate of aspiration pneumonia in hospitalized Parkinson’s disease patients: a cross-sectional study.
BMC neurology. 15 [DOI] 10.1186/s12883-015-0362-9. [PMID] 26141135.
2014
Shorter Pulse Generator Longevity and More Frequent Stimulator Adjustments With Pallidal DBS for Dystonia Versus Other Movement Disorders
Brain Stimulation. 7(3):345-349 [DOI] 10.1016/j.brs.2014.01.008. [PMID] 24548586.

Grants

Oct 2020 ACTIVE
Adaptive DBS Algorithm for Personalized Therapy in Parkinsons Disease (ADAPT-PD) Trial
Role: Principal Investigator
Funding: MEDTRONIC INC
Jul 2019 – Jul 2024
Retrospective Multi-Site Re-Evaluation of the MRI-Defined STN and Its Correlation to Motor Outcomes With Stimulation Treatment
Role: Principal Investigator
Funding: SURGICAL INFORMATION SCIENCES
Aug 2018 – Aug 2023
Local Field Potential Beta Adaptive Deep Brain Stimulation Feasibility Study (LFP Beta aDBS Feasibility Study)
Role: Principal Investigator
Funding: MEDTRONIC INC
Jul 2017 – Jul 2022
Post Market Clinical Follow Up Evaluating the Infinity Deep Brain Stimulation Implantable Pulse Generator System
Role: Principal Investigator
Funding: ST JUDE MEDICAL

Education

Fellowship, Movement Disorders
2015-2016 · University of Florida
Residency, Neurology
2010-2014 · University of Alabama at Birmingham
Master's Degree, Medicine and Health
2009-2010 · Universidade Federal da Bahia
Medical Degree
2002-2008 · Universidade Federal da Bahia

Contact Details

Phones:
Business:
(352) 294-5000
Emails:
Business:
l.almeida@ufl.edu
Addresses:
Business Mailing:
PO Box 100268
GAINESVILLE FL 32610
Business Street:
3011 SW WILLISTON RD RM 1103
GAINESVILLE FL 32608