Matthew R Burns

Matthew R Burns, MD, PhD

Assistant Professor Of Neurology

Department: MD-NEUROLOGY-MOVEMENT DISORDER
Business Phone: (352) 294-5000
Business Email: mburns1@ufl.edu

About Matthew R Burns

My name is Matthew Burns, MD, PhD, and I am a board-certified neurologist and movement disorders specialist at the Norman Fixel Institute for Neurological Diseases at UF Health, serving as an assistant professor in the University of Florida Department of Neurology.

I received my medical and doctorate degrees from the University of Illinois College of Medicine at Chicago in 2012. I went on and completed my neurology residency at the University of Chicago Medical Center in 2018 and my movement disorders fellowship at UF in 2021.

In clinic, I see patients for a variety of movement disorders including dystonia, tremor disorders and ataxia. When I’m not seeing patients in clinic, I run a National Institutes of Health-funded lab focused on the non-motor symptoms of neurodegenerative disorders, the molecular mechanisms of aging and neuromodulation.

As a clinician and a researcher, I aim to translate my knowledge of the molecular mechanisms of neurodegenerative disease, high-field imaging, brain machine interface and electrophysiology into therapies for patients who have movement disorders and dementia.

In my free time, I enjoy exercising, playing piano and helping coach my kids’ little league teams.

Related Links:

Teaching Profile

Courses Taught
2022
MDU4002 Introduction to Medical Science Seminar 2
2022-2023
PAS5020 Intro to Medicine 2
2022-2023
GMS6905 Independent Studies in Medical Sciences
2023-2024
GMS6090 Research in Medical Sciences
2024-2025
GMS6971 Research for Master’s Thesis

Board Certifications

  • Neurology
    American Board of Psychiatry and Neurology

Clinical Profile

Specialties
  • Neurology
Areas of Interest
  • Acute cerebellar ataxia
  • Ataxia
  • Deep brain stimulation
  • Dystonia
  • Essential tremor
  • Friedreich ataxia
  • Movement – uncontrollable
  • Movement – uncontrolled or slow
  • Movement – uncoordinated
  • Movement – unpredictable or jerky
  • Parkinson Disease
  • Tremor disorders

Research Profile

Areas of Interest
  • Deep brain stimulation
  • Dementia
  • Electrophysiology
  • Neurodegenerative diseases
  • ataxia
  • mechanisms of aging
  • neuromodulatory treatments

Publications

Academic Articles
2024
Emerging therapies in hereditary ataxias.
Trends in molecular medicine. [DOI] 10.1016/j.molmed.2024.07.008. [PMID] 39153956.
2024
Fatigue Impacts Quality of Life in People with Spinocerebellar Ataxias.
Movement disorders clinical practice. 11(5):496-503 [DOI] 10.1002/mdc3.14006. [PMID] 38419568.
2024
Pictures at an exhibition: A commentary on Benn & Robinson (2024).
Cognitive, affective & behavioral neuroscience. 24(2):368-369 [DOI] 10.3758/s13415-024-01174-z. [PMID] 38472614.
2022
Evolving Concepts in Our Understanding and Treatment of Holmes Tremor, Over 100 Years in the Making
Tremor and Other Hyperkinetic Movements. 12(1) [DOI] 10.5334/tohm.683. [PMID] 35651920.
2022
Inherited Ataxias in Children.
Pediatric neurology. 131:54-62 [DOI] 10.1016/j.pediatrneurol.2022.04.004. [PMID] 35490578.
2022
Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease.
Brain communications. 4(4) [DOI] 10.1093/braincomms/fcac165. [PMID] 35822101.
2022
TANGO2 Mutation: A Genetic Cause of Multifocal Combined Dystonia.
Movement disorders clinical practice. 9(3):380-382 [DOI] 10.1002/mdc3.13400. [PMID] 35402644.
2021
Advances and Future Directions of Neuromodulation in Neurologic Disorders.
Neurologic clinics. 39(1):71-85 [DOI] 10.1016/j.ncl.2020.09.004. [PMID] 33223090.
2021
An Update on Botulinum Toxin in Neurology.
Neurologic clinics. 39(1):209-229 [DOI] 10.1016/j.ncl.2020.09.014. [PMID] 33223084.
2021
Deep brain stimulation programming strategies: segmented leads, independent current sources, and future technology
Expert Review of Medical Devices. 18(9):875-891 [DOI] 10.1080/17434440.2021.1962286.
2021
Disparities in diagnosis, treatment and survival between Black and White Parkinson patients
Parkinsonism & Related Disorders. 87:7-12 [DOI] 10.1016/j.parkreldis.2021.04.013.
2020
Co-occurrence of apathy and impulse control disorders in Parkinson disease.
Neurology. 95(20):e2769-e2780 [DOI] 10.1212/WNL.0000000000010965. [PMID] 33004605.
2020
Current Management and Emerging Therapies in Multiple System Atrophy.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 17(4):1582-1602 [DOI] 10.1007/s13311-020-00890-x. [PMID] 32767032.
2020
Deep Brain Stimulation Impedance Decreases Over Time Even When Stimulation Settings Are Held Constant.
Frontiers in human neuroscience. 14 [DOI] 10.3389/fnhum.2020.584005. [PMID] 33240066.
2020
Functional and Structural Connectivity Patterns Associated with Clinical Outcomes in Deep Brain Stimulation of the Globus Pallidus Internus for Generalized Dystonia
American Journal of Neuroradiology. 41(3):508-514 [DOI] 10.3174/ajnr.a6429.
2020
High-dose Botulinum Toxin Therapy: Safety, Benefit, and Endurance of Efficacy.
Tremor and other hyperkinetic movements (New York, N.Y.). 10 [DOI] 10.7916/tohm.v0.749. [PMID] 32149014.
2020
Neuroimaging Advances in Deep Brain Stimulation: Review of Indications, Anatomy, and Brain Connectomics
American Journal of Neuroradiology. 41(9):1558-1568 [DOI] 10.3174/ajnr.a6693.
2020
Using rodent models to understand interactions between gambling and substance use.
Current opinion in behavioral sciences. 31:37-41 [DOI] 10.1016/j.cobeha.2019.10.012. [PMID] 33102640.
2019
Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson’s Disease.
Tremor and other hyperkinetic movements (New York, N.Y.). 9 [DOI] 10.7916/tohm.v0.685. [PMID] 31565536.
2015
Calcinosis cutis presenting in the context of long-term therapy for chronic myeloid leukemia: a case report and review of the literature.
Wounds : a compendium of clinical research and practice. 27(2):20-5 [PMID] 25785904.
2011
Microtubule-severing ATPase spastin in glioblastoma: increased expression in human glioblastoma cell lines and inverse roles in cell motility and proliferation.
Journal of neuropathology and experimental neurology. 70(9):811-26 [DOI] 10.1097/NEN.0b013e31822c256d. [PMID] 21865889.

Grants

Apr 2024 ACTIVE
Contribution of Repeat Associated Non-AUG (RAN) Proteins in Friedreich's and Other Hereditary Ataxias
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Mar 2023 – Apr 2024
Cognito Master Student Salary Support (Neuroscience)
Role: Principal Investigator
Funding: COGNITO THERAPEUTICS
Mar 2022 – Feb 2023
Assessment of diffusion imaging metrics in cerebellar tracts as a quantitative marker of disease progression in SCA
Role: Principal Investigator
Funding: NATL ATAXIA FOUNDATION
Jul 2021 ACTIVE
Contribution of RAN proteins to HD, SCA3 other CAG.CTG expansion diseases
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Jul 2021 – Feb 2023
Cognitive and Motivational Network Dysfunction & Neuromodulation in Aging and Synucleinopathy
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2021 – Dec 2022
Cognitive and Motivational Network Dysfunction & Neuromodulation in Aging and Synucleinopathy
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2021 – Jul 2021
Optogenetic Modulation of Mesocorticolimbic Brain Networks as a Treatment for Parkinsons Disease Cognitive Dysfunction
Role: Principal Investigator
Funding: AMER ACAD OF NEUROLOGY
May 2021 ACTIVE
Cognitive and Affective Network Dysfunction and Neuromodulation in Aging and Synucleinopathy
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jan 2020 – Jun 2021
Modulation of Synuclein Pathology Through Induction of Gamma Band Oscillations in a Mouse Model of DLB
Role: Principal Investigator
Funding: UF FOUNDATION
Jun 2019 – May 2021
DRPD-ROF2019: A Microfluidics Optrode: A Next Generation Approach to Brain Network Modulation in Parkinsons Disease
Role: Principal Investigator
Funding: UF RESEARCH

Education

Fellowship, Movement Disorders
2018 · University of Florida
Residency, Neurology
2015-2018 · University of Chicago Medical Center
Doctorate Degree, Philosophy and Neuroscience
2007-2012 · University of Illinois College of Medicine at Chicago
Medical Degree
2005-2012 · University of Illinois College of Medicine at Chicago
Bachelor of Arts, Physics and Religion
1996-2001 · Oberlin College

Contact Details

Phones:
Business:
(352) 294-5000
Emails:
Business:
mburns1@ufl.edu
Addresses:
Business Mailing:
PO Box 100236
GAINESVILLE IL 32610
Business Street:
1149 NEWELL DR RM L2 # 140
GAINESVILLE FL 32610